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Dopamine DNA health report

Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Dopamine and see a list of existing studies.

SNP polymorphisms related to the topic Dopamine:

rs686Affects dopamine D1 receptors associated with autism spectrum disorders.
rs4532Affects dopamine D1 receptors associated with autism spectrum disorders.
rs4633Catechol-O-methyltransferase deficiency is associated with total plasma homocysteine levels and may increase the risk of venous thrombosis.
rs5320Associated with attention deficit hyperactivity disorder in children.
rs5322
rs5326D1 dopamine receptor gene is associated with the length of the interval between first heroin use and onset of dependence in heroin addicts. Also influences the increased risk of salt-sensitive hypertension.
rs6265Increased risk of ADHD or depression. Slightly faster decline in mental abilities in patients with Alzheimer's disease. The presence of this BDNF polymorphism is associated with differences in brain motor system functioning, altered short-term plasticity, and greater error in short-term motor learning.
rs6269Catechol-O-methyltransferase (COMT) breakdown is associated with increased pain sensitivity in humans and in the development of chronic widespread pain, fibromyalgia.
rs6277Associated with a 1.6-fold increased risk of schizophrenia.
rs6280A polymorphism of the dopamine D3 receptor gene is associated with chronic schizophrenia or schizoaffective disorder.
rs6347A functional variant of the dopamine transporter gene associated with the development of schizophrenia
rs26907The polymorphism is associated with increased alcohol dependence.
rs270722-fold risk of severe alcohol withdrawal. Associated with more severe symptoms after alcohol withdrawal, such as seizures and white fever. Possible increased chance of ADHD.
rs77905
rs165599Genetic variability in COMT increases the risk of psychotic and affective disorders.
rs167770
rs167771The dopamine receptor-3 (DRD3) gene is associated with specific repetitive behaviours in autism spectrum disorders.
rs216013
rs265981Affects dopamine D1 receptors associated with autism spectrum disorders.
rs324026
rs324420The genetic variant FAAH is associated with problematic drug use, namely marijuana, opioids, and methamphetamine.
rs460000
rs752306Genetic polymorphism of the dopamine D4 receptor increases the risk of attention deficit hyperactivity disorder in children.
rs921451Polymorphism of the dopamine transporter type 1 gene alters response to treatment in Parkinson's disease.
rs968529
rs1006737A polymorphism of the potential-dependent calcium channel gene CACNA1C, is associated with risk of bipolar disorder, schizophrenia and other psychiatric disorders.
rs1049353Genetic variability in cannabinoid receptor 1 (CNR1) causes addiction to cannabis. Also associated with weight gain when taking neuroleptics.
rs1076560A variant of the dopamine D2 receptor gene increases the risk of early Parkinson's disease.
rs1076563
rs1079597DRD2 polymorphisms confer an increased risk of autism spectrum disorders and schizophrenia.
rs1079598Associated with weight gain caused by antipsychotic drugs (neuroleptics).
rs1108580Dopaminergic pathway gene polymorphism and genetic predisposition to Parkinson's disease and schizophrenia.
rs1108581
rs1125394The DRD2 polymorphism modulates reward and emotion processing, dopamine neurotransmission, and openness to experience.
rs1486009Risk of developing an opioid use disorder (OUD).
rs1541332
rs1611115Associated with lower plasma dopamine beta-hydroxylase activity, increased risk of Parkinson's disease, ADHD.
rs1611123A gene variant that increases nicotine dependence and difficulty quitting smoking.
rs1799978The dopamine D2 receptor gene is associated with weight gain in schizophrenic patients with long-term treatment with neuroleptics.
rs1800497TaqIA polymorphisms of the DRD2 dopamine D2 receptor gene are associated with concomitant alcohol use and depressive disorders.
rs1800499
rs2007153Polymorphisms associated with Alzheimer's disease, Parkinson's disease and schizophrenia.
rs2159100A polymorphism of the potential-dependent calcium channel gene CACNA1C, is associated with risk of bipolar disorder, schizophrenia and other psychiatric disorders.
rs2242446Risk of orthostatic intolerance - dizziness or fainting that occurs with prolonged standing or upright posture.
rs2283265Functional variants of the dopamine receptor gene are a potential factor in neuropsychiatric disorders.
rs2295193A variant of the estrogen receptor I (ESR1) gene is associated with anorexia nervosa and eating disorders.
rs2302729
rs2440390
rs2519154
rs2617605
rs2734833
rs2734838
rs3025382The polymorphism is associated with increased nicotine dependence.
rs3025399
rs3025422
rs3735273
rs3773678
rs3776512
rs3785143A variant of a rare protective allele in the norepinephrine transporter gene causes risk of attention deficit hyperactivity disorder.
rs4436578The dopamine D2 receptor gene is associated with weight gain in schizophrenic patients with long-term treatment with neuroleptics.
rs4460839
rs4648317Tendency to higher nicotine dependence, increased impulsivity and thrill-seeking.
rs4703822
rs4867798Breakage of the dopamine D1 receptor gene increases the risk of paranoid schizophrenia.
rs7633291
rs7876027
rs8044769
rs9288993
rs9824856
rs10761482Association of the ANK3 risk allele with cognitive ability and bipolar disorder.
rs10993949
rs10994336Ankyrin variant 3 (ANK3) is an independent genetic risk factor for bipolar disorder.
rs11214606
rs12363125
rs12364283The striatal polymorphism of the D2 receptor is a novel genetic marker of multiple addiction phenotypes: alcohol, nicotine, heroin and opioid dependence.
rs17030795
rs17410422
rs28363168
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