SNP information rs2283265

Research and publications:

  18077373   Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

  18332877   Family-based association testing strongly implicates DRD2 as a risk gene for schizophrenia in Han Chinese from Taiwan.

  18829695   Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia.

  19321766   Dopamine DRD2 polymorphism alters reversal learning and associated neural activity.

  19393722   Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms.

  19772578   Two-stage case-control association study of dopamine-related genes and migraine.

  20179754   Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance.

  20617039   Alcoholism and alternative splicing of candidate genes.

  20736885   PharmGKB summary: dopamine receptor D2.

  20881944   The roles of dopamine and serotonin in decision making: evidence from pharmacological experiments in humans.

  21150907   Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.

  21289622   Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy.

  21438146   Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.

  21527290   Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.

  22424959   DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience.

  22579533   Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes.

  22963930   Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.

  23097719   Current perspectives on the neurobiology of drug addiction: a focus on genetics and factors regulating gene expression.

  23340505   Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction.

  23635803   ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse.

  23856854   Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders.

  24001007   Polymorphisms in the dopamine receptor 2 gene region influence improvements during working memory training in children and adolescents.

  24322206   Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain.

  24410775   Moderator effects of working memory on the stability of ADHD symptoms by dopamine receptor gene polymorphisms during development.

  24495967   Common polymorphisms in dopamine-related genes collectively cause “schizophrenia-like” prefrontal hypoactivity.

  24780147   Association of dopamine gene variants, emotion dysregulation and ADHD in autism spectrum disorder.

  24819610   DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  25875614   Overlapping dopaminergic pathway genetic susceptibility to heroin and cocaine addictions in African Americans.

  25955176   Polymorphic variants in the dopamine receptor D2 in women with endometriosis-related infertility.

  26926883   Genetic variation and dopamine D2 receptor availability: a systematic review and meta-analysis of human in vivo molecular imaging studies.

  27190009   Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study.

  27757066   Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.

  27933030   The Association of DRD2 with Insight Problem Solving.

  28692418   Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese.

  28927418   A systematic review and integrative approach to decipher the overall molecular link between levodopa response and Parkinson's disease.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30367264   Effects of DRD2 splicing-regulatory polymorphism and DRD4 48 bp VNTR on crack cocaine addiction.

  30847741   DRD2 Genotype-Based Variants Modulates D2 Receptor Distribution in Ventral Striatum.

  30967134   A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia.

  31025317   Significant association of DRD2 enhancer variant rs12364283 with heroin addiction in a Pakistani population.

  31559529   Influence of dopamine-related genes on craving, impulsivity, and aggressiveness in Korean males with alcohol use disorder.

  33039854   Contribution of dopamine D2 and D3 receptor functional variants to motor and non-motor symptoms of early-onset Parkinson's disease.

  33529975   Cortical mediation of relationships between dopamine receptor D2 and cognition is absent in youth at risk of bipolar disorder.

  33807560   A Systematic Review of Genetic Polymorphisms Associated with Binge Eating Disorder.

  34151861   Clinical and genetic analysis of psychosis in Parkinson's disease.

  34453125   Molecular genetics of cocaine use disorders in humans.

  35044623   The role of single nucleotide polymorphisms of monoamine oxidase B, dopamine D2 receptor, and DOPA decarboxylase receptors among patients treated for Parkinson's disease.

  35398727   Correlation between genetic factors and freezing of gait in patients with Parkinson's disease.