Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Obsessive-compulsive disorder (OCD) and see a list of existing studies.
SNP polymorphisms related to the topic Obsessive-compulsive disorder (OCD):
|Glutamate receptor gene (GRIN2B) associated with reduced glutamatergic concentration in the anterior cingulate gyrus in obsessive-compulsive disorder in children.
|The study showed a 10% increase in total plasma homocysteine (tHcy)
|Increased risk of ADHD or depression. Slightly faster decline in mental abilities in patients with Alzheimer's disease. The presence of this BDNF polymorphism is associated with differences in brain motor system functioning, altered short-term plasticity, and greater error in short-term motor learning.
|Associated with a 1.6-fold increased risk of schizophrenia.
|Serotonin transporter and serotonin receptor gene polymorphisms are associated with susceptibility to substance abuse.
|Genetic factors specific to obsessive-compulsive disorder.
|TPH-2 polymorphisms affect response to treatment with antidepressants and SSRIs.
|The serotonin receptor gene HTR2A polymorphism is associated with bipolar affective disorder and autism spectrum disorder.
|The serotonin transporter rs25531 polymorphism is associated with neuroticism, depression, OCD, ADHD and autism spectrum disorder.
|Each C rs25532 allele accounts for increased serotonin transporter function and is pathogenetically associated with OCD.
|2-fold risk of severe alcohol withdrawal. Associated with more severe symptoms after alcohol withdrawal, such as seizures and white fever. Possible increased chance of ADHD.
|A variant of the serotonin transporter gene (SLC6A4) is associated with suicidal behaviour in schizophrenic patients.
|The dopamine receptor-3 (DRD3) gene is associated with specific repetitive behaviours in autism spectrum disorders.
|Association between the glutamate transporter gene SLC1A1 and early onset of obsessive-compulsive disorder.
|Fear reactivation and symptoms of combat-related PTSD: specificity and preliminary study of the effect of the 5-HT3A receptor gene.
|The DRD2 polymorphism modulates reward and emotion processing, dopamine neurotransmission, and openness to experience.
|Common variants of the HTR3 gene are associated with obsessive-compulsive disorder.
|Variants in the tryptophan hydroxylase gene involved in the development and treatment of opiate, heroin and cocaine addiction.
|The glutamate receptor gene GRIN2B associated with reduced glutamatergic concentration in the anterior cingulate cortex in obsessive-compulsive disorder in children.
|Breakage of the tryptophan hydroxylase 2 (TPH2) gene associated with attention deficit hyperactivity disorder.
|Polymorphisms of the gene encoding serotonin 2A receptor affect response to antidepressant treatment.
|A functional serotonin transporter gene polymorphism is associated with major depression, schizophrenia and ADHD.
|Association between the SLC1A1 gene and early onset of obsessive-compulsive disorder.
|Functional variants of the dopamine receptor gene are a potential factor in neuropsychiatric disorders.
|A haplotype containing quantitative trait loci of SLC1A1 gene expression is associated with obsessive-compulsive disorder.
|Serotonin receptor gene HTR2A polymorphism is associated with panic disorder features.
|Association of the glutamate transporter gene SLC1A1 with atypical obsessive-compulsive symptoms induced by neuroleptics.
|The TPH2 gene variant is associated with attention-deficit/hyperactivity disorder.
|Tendency to higher nicotine dependence, increased impulsivity and thrill-seeking.
|Association with major depression and response to antidepressants. The polymorphism is associated with selective serotonin and serotonin-norepinephrine reuptake inhibitor response in depressive disorder.
|Associations of the serotonin receptor gene HTR2A with bipolar disorder and major depressive disorder.
|Breakage of the tryptophan hydroxylase gene promotes dishonest behaviour.
|A genetic polymorphism of the serotonin transporter gene, SLC6A4 rs16965628, is associated with obsessive-compulsive disorder.
|The gene breakage is linked to bipolar affective disorder.
|A polymorphism in the serotonin transporter locus (SLC6A4) predisposes to autism and compulsive rigid behaviour.