Normal allele: TT
The DRD2 polymorphism modulates reward and emotion processing, dopamine neurotransmission, and openness to experience.
Polymorphism rs1125394 is related to topics like this:
Research and publications:
20736885 PharmGKB summary: dopamine receptor D2.
21245293 Correlated genotypes in friendship networks.
21906503 Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.
22287936 Pharmacogenetics of antipsychotic treatment response and side effects.
22963930 Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.
26753847 Parent and peer influences on emerging adult substance use disorder: A genetically informed study.
27247849 Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.
30093869 Biological Predictors of Clozapine Response: A Systematic Review.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.