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SNP information rs1125394

RS1125394

Normal allele: TT

The DRD2 polymorphism modulates reward and emotion processing, dopamine neurotransmission, and openness to experience.

Polymorphism rs1125394 is related to topics like this:

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...

Is OCD obsessive compulsive disorder genetic

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by features known as...

ADHD is it genetic

ADHD, a behavioral disorder that usually commences during childhood, is marked by a brief attention...


Research and publications:

  15830237   Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations.

  16278074   Dopamine D2 receptor gene variants and quantitative measures of positive and negative symptom response following clozapine treatment.

  18077373   Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

  19693267   Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

  19968402   Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.

  20736885   PharmGKB summary: dopamine receptor D2.

  21143246   Neurotransmitter and neuromodulator genes associated with a history of depressive symptoms in individuals with alcohol dependence.

  21150907   Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.

  21245293   Correlated genotypes in friendship networks.

  21906503   Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.

  22287936   Pharmacogenetics of antipsychotic treatment response and side effects.

  22424959   DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience.

  22963930   Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.

  26753847   Parent and peer influences on emerging adult substance use disorder: A genetically informed study.

  27247849   Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

  29992684   A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

Mitochondria dna

The mitochondria contain circular chromosomes known as mitochondrial DNA and are organelles...

Diseases genetic

Human genetic illnesses stem from mutations in one or more genes and can be classified as occurring...

Type 2 diabetes genetic

Type 2 diabetes is the most prevalent and impactful subtype of diabetes worldwide, affecting around...

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