Normal allele: CC
Increased risk of ADHD or depression. Slightly faster decline in mental abilities in patients with Alzheimer's disease. The presence of this BDNF polymorphism is associated with differences in brain motor system functioning, altered short-term plasticity, and greater error in short-term motor learning.
Polymorphism rs6265 is related to topics like this:
Research and publications:
16344533 BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study
17096834 No association between polymorphisms in the BDNF gene and age at onset in Huntington disease
17196936 Brain-derived neurotrophic factor and risk of schizophrenia: an association study and meta-analysis
17212826 TAMGeS: a Three-array Method for Genotyping of SNPs by a dual-colour approach.
17293537 Brain-derived neurotrophic factor genetic variants associated with Alzheimer's disease.
17483451 Gene-gene interaction associated with neural reward sensitivity
17602759 Immune cell BDNF secretion is associated with white matter volume in multiple sclerosis
17653045 Candidate gene and locus analysis of myopia
17894414 BDNF Val66Met variant and age of onset in schizophrenia.
18205169 Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis
18478177 Investigation of the functional brain-derived neurotrophic factor gene variant Val66MET in migraine
18534558 Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence.
18704161 Genetic variation in an individual human exome.
18776599 Susceptibility genes for gentamicin-induced vestibular dysfunction.
18813964 Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta.
18830724 Assessing case-control associations of Alzheimer's disease using family-based methods.
18957941 Genome-wide association scan for five major dimensions of personality.
19018231 Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder
19236730 Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response
19295238 Association analysis of brain-derived neurotrophic factor gene polymorphisms in asthmatic families
19336781 Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes.
19388013 BDNF, relative preference, and reward circuitry responses to emotional communication
19403460 Pharmacogenetics of antidepressant response: an update.
19721723 Brain-derived neurotrophic factor: role in depression and suicide.
19734545 A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
19797905 Allelic based gene-gene interaction in case-control studies
19895626 The effect of BDNF gene variants on asthma in German children
19953912 [An association study of brain-derived neurotrophic factor gene polymorphism in bipolar disorders]
20042999 BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism
20075215 A genetic variant BDNF polymorphism alters extinction learning in both mouse and human
20125193 Common genetic variation and performance on standardized cognitive tests.
20127379 From monogenic to polygenic obesity: recent advances.
20147969 Non-synonymous single-nucleotide polymorphisms associated with blood pressure and hypertension
20159343 The genetics of major depression: moving beyond the monoamine hypothesis.
20172611 Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder
20191112 The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.
20418890 Genome-wide meta-analyses identify multiple loci associated with smoking behavior
20456319 Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia.