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Omega 3 genetics


If you tested your DNA with a personal genomics service like 23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage or another testing company, you can learn more about your risk factors for hundreds of diseases. By clicking the button above ⬆️, you can upload your raw DNA data file and receive a personalized 250-page health report with research links that is the most comprehensive.

It may seem counterintuitive that substances with the names "fat" and "acid" can be beneficial for your health, but omega-3 fatty acids are essential when it comes to keeping your heart in good shape. These polyunsaturated fats must come from either supplements or a balanced diet because they're indispensable to everyone's well-being. In cases where you have an insufficient level of this kind of fat, there might arise some food limitations which should be taken into account. By using AncestryDNA®+Traits service, you will learn if potentially existing genetic factors could play a minor role in determining the levels of Omega 3s found in your body systems.

The quantity of omega-3s in your body relies heavily on your diet as these essential fatty acids are primarily obtained from food.

According to research, genes also have a minor influence. AncestryDNA examines the genes that impact four of the 11 recognized variations of omega-3s. Currently, only two genetic indicators are believed to moderately affect omega-3 levels: The ELOVL2 gene on chromosome 6 and the FADS1 gene on chromosome 11.

Despite having made some progress, genetics and nutrition research remains at an early stage. Scientists may still not have discovered all genes that are linked to omega-3 fatty acid levels.

Discover your omega-3 levels based on your DNA through our Health TenDNA report.

Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Omega-3, unsaturated fatty acids and see a list of existing studies.

SNP polymorphisms related to the topic Omega-3, unsaturated fatty acids:

rs174546Variations in the FADS1 gene interact with and are associated with changes in fatty acid composition in cortical tissue.
rs174575Variants in the FADS gene modify the relationship between fish consumption and docosahexaenoic acid content in breast milk. This in turn affects the child's cognitive function and hyperactivity/attention problems.
rs174448The gene polymorphism alters EPA and DHA levels and their effects in brain development and function.
rs174550The fatty acid desaturase (FADS) gene polymorphism is associated with insulin resistance, type 2 diabetes and impaired fasting glucose levels in adults.
rs3834458Single nucleotide polymorphism rs3834458 affects levels of n-3 long-chain polyunsaturated fatty acids.
rs174548Polymorphisms in this gene are associated with decreased levels of omega-3 fatty acids, increased relative levels of omega-6 fatty acids and increased concentrations of trans-unsaturated fatty acids. In vegetarians, some polymorphisms of this gene may result in an undesirable situation associated with increased inflammation.
rs174537Polymorphisms in the fatty acid desaturase (FADS) gene cluster modify the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles.
rs174553Polymorphisms in the fatty acid desaturase (FADS) gene cluster can modify the effects of fish oil supplementation on the fatty acid profile of blood and erythrocytes.
rs174547Genetic variants that affect circulating lipid levels and risk of cardiovascular disease. People with the C gene variant have lower levels of long forms of fatty acids such as AA. Vegetarians and vegans with the C gene variant have lower plasma concentrations of EPA, DHA and AA than omnivores. Vegetarians with the C gene variant have been shown to benefit from omega-3 supplements or omega-3 rich foods such as chia seeds, flax seeds and canola oil.
rs174570Genetic polymorphisms of FADS are associated with fatty acid metabolism through changes in DNA methylation and gene expression.
rs174583Fatty acid desaturase gene polymorphism increases insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition.
rs498793Fatty acid desaturase gene breakage increases the manifestations of attention-deficit/hyperactivity disorder.
rs1535FADS2 polymorphisms affect blood levels of omega-3 and omega-6 polyunsaturated fatty acids during pregnancy, at birth, and at age 7 years.
rs174556FADS gene polymorphisms increase arachidonic acid levels and risk of Alzheimer's disease.
rs174561FADS gene polymorphism alters serum glycerophospholipid fatty acid concentrations and their percentage composition in children.
rs953413ELOVL2 gene polymorphisms are associated with increased proportions of eicosapentaenoic and docosahexaenoic acids in plasma after fish oil intake.
rs174602Determines the effect of omega-3 fatty acids on the biomarker activity of metals and persistent organic pollutants.
rs2277324Affects changes in blood levels of polyunsaturated fatty acids.
rs16940765Affects changes in blood levels of polyunsaturated fatty acids.
rs17718324Affects changes in blood levels of polyunsaturated fatty acids.
rs7744440Affects changes in blood levels of polyunsaturated fatty acids.