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SNP information rs174583

RS174583

Normal allele: CC

Fatty acid desaturase gene polymorphism increases insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition.

Polymorphism rs174583 is related to topics like this:

Omega 3 genetics

It may seem counterintuitive that substances with the names "fat" and "acid" can be beneficial for...

Research and publications:

  18936223   Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation.

  20339536   Genome-wide association of lipid-lowering response to statins in combined study populations.

  20395685   Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study.

  20562440   FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.

  20565855   Genetic variation in lipid desaturases and its impact on the development of human disease.

  21513558   Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study.

  22960237   Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males.

  24240437   Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young.

  28555039   FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.

  28598979   Association of maternal weight with FADS and ELOVL genetic variants and fatty acid levels- The PREOBE follow-up.

  29491470   Dietary n-3 and n-6 polyunsaturated fatty acids, the FADS gene, and the risk of gastric cancer in a Korean population.

  29937909   The effect of FADS2 gene rs174583 polymorphism on desaturase activities, fatty acid profile, insulin resistance, biochemical indices, and incidence of type 2 diabetes.

  30407633   Triacylglycerol-Lowering Effect of Docosahexaenoic Acid Is Not Influenced by Single-Nucleotide Polymorphisms Involved in Lipid Metabolism in Humans.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

CPT2 disease

A condition affecting the oxidation of long-chain fatty acids, Carnitine palmitoyltransferase II...

Nuclear hormone receptors

The activated ligand-regulated transcription factors collectively known as nuclear receptors...

21 hydroxylase

The CYP21A2 gene encodes the human protein, Steroid 21-hydroxylase. This enzyme hydroxylates...

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