SNP information rs3834458

Research and publications:

  19546342   A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1.

  19996744   Fatty acid interactions with genetic polymorphisms for cardiovascular disease.

  20335541   FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk.

  20427696   Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.

  20565855   Genetic variation in lipid desaturases and its impact on the development of human disease.

  20948998   Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life.

  21629299   Fatty acid desaturase 2 promoter mutation is not responsible for Δ6-desaturase deficiency.

  21793953   FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children.

  21818279   Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children.

  22563332   Fatty Acid desaturase gene variants, cardiovascular risk factors, and myocardial infarction in the costa rica study.

  22629455   FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies.

  23160180   Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.

  23285256   Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism.

  23636240   FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants.

  24067669   Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age.

  26474818   Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study.

  26742060   DHA Effects in Brain Development and Function.

  26891335   Cancer Risk and Eicosanoid Production: Interaction between the Protective Effect of Long Chain Omega-3 Polyunsaturated Fatty Acid Intake and Genotype.

  27004414   Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease.

  28259851   Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI).

  28552045   Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians.

  30103441   Associations between Fatty Acid Intake and Status, Desaturase Activities, and FADS Gene Polymorphism in Centrally Obese Postmenopausal Polish Women.

  31487670   Effects of the rs3834458 Single Nucleotide Polymorphism in FADS2 on Levels of n-3 Long-chain Polyunsaturated Fatty Acids: A Meta-analysis.

  31568926   Maternal polymorphisms in the FADS1 and FADS2 genes modify the association between PUFA ingestion and plasma concentrations of omega-3 polyunsaturated fatty acids.

  31781193   Association of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease with FADS2 rs3834458 Gene Polymorphism in the Chinese Han Population.

  32433731   Maternal Long-Chain Polyunsaturated Fatty Acid Status, Methylmercury Exposure, and Birth Outcomes in a High-Fish-Eating Mother-Child Cohort.

  32622152   Metabolic syndrome in postmenopausal women is associated with lower erythrocyte PUFA/MUFA and n-3/n-6 ratio: A case-control study.

  32725293   The influence of fish consumption on serum n-3 polyunsaturated fatty acid (PUFA) concentrations in women of childbearing age: a randomised controlled trial (the iFish Study).

  33526157   Maternal and child fatty acid desaturase genotype as determinants of cord blood long-chain PUFA (LCPUFA) concentrations in the Seychelles Child Development Study.