Normal allele: CC
Polymorphisms in this gene are associated with decreased levels of omega-3 fatty acids, increased relative levels of omega-6 fatty acids and increased concentrations of trans-unsaturated fatty acids. In vegetarians, some polymorphisms of this gene may result in an undesirable situation associated with increased inflammation.
Polymorphism rs174548 is related to topics like this:
Research and publications:
19043545 Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.
20081858 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
20864672 Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
23028684 Adaptive evolution of the FADS gene cluster within Africa.
24665059 Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population.
28555039 FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.