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Vitamin B4 (choline) DNA health report

Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Vitamin B4 (choline) and see a list of existing studies.

SNP polymorphisms related to the topic Vitamin B4 (choline):

rs7946Genetic polymorphisms in methyl group metabolism DNA methylation in peripheral blood. Affect the human need for choline (vitamin B4).
rs174548Polymorphisms in this gene are associated with decreased levels of omega-3 fatty acids, increased relative levels of omega-6 fatty acids and increased concentrations of trans-unsaturated fatty acids. In vegetarians, some polymorphisms of this gene may result in an undesirable situation associated with increased inflammation.
rs211699
rs649352
rs671919
rs750546
rs1036950
rs1051266The protein encoded by the gene transports folic acid into the cell and thus plays a role in the intracellular regulation of folate concentration. In this genotype, folate absorption is worse. Folic acid requirement is higher. Alcohol consumption is more critical for the risk of vitamin B9 deficiency.
rs1880676Genetic variability in the choline-O-acetyltransferase gene influences increased risk of depression and Alzheimer's disease.
rs2236225Possible increased risk of fetal birth defects. A 1.5-fold higher risk for Caucasian mothers to give birth to children with DNT (neural tube defect). The association in children with this mutation with an increased risk of heart defects is greater if their mother did not get enough folic acid during pregnancy. The risk is reduced with adequate levels of folic acid and vitamin B6.
rs2289205Choline pathway gene polymorphism increases the risk of intrauterine foetal death.
rs3760188
rs4244593
rs4646343
rs4646404
rs4646409
rs4949874
rs6658825
rs7520974
rs10493565
rs10874305
rs11578532
rs12325817
rs12738260
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