SNP information rs174570

Research and publications:

  19060911   Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

  19798445   Genetic determinants of circulating sphingolipid concentrations in European populations.

  19919681   Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq.

  19944404   Genomic dissection of population substructure of Han Chinese and its implication in association studies.

  19951432   Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease

  20427696   Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.

  20445095   Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency.

  20484448   Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study.

  20502693   Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

  20562440   FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.

  20565855   Genetic variation in lipid desaturases and its impact on the development of human disease.

  21303902   Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol.

  21383846   Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.

  21507254   Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.

  21513558   Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  22073310   Association of genetic loci with blood lipids in the Chinese population.

  22563332   Fatty Acid desaturase gene variants, cardiovascular risk factors, and myocardial infarction in the costa rica study.

  22701466   Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos.

  23468967   Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

  24240437   Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young.

  24956270   Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants.

  25367143   Effects of FADS and ELOVL polymorphisms on indexes of desaturase and elongase activities: results from a pre-post fish oil supplementation.

  26833210   Evaluation of pleiotropic effects among common genetic loci identified for cardio-metabolic traits in a Korean population.

  26879377   FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome.

  27188529   Positive Selection on a Regulatory Insertion-Deletion Polymorphism in FADS2 Influences Apparent Endogenous Synthesis of Arachidonic Acid.

  27341449   Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders.

  28253292   Polymorphisms associated with a tropical climate and root crop diet induce susceptibility to metabolic and cardiovascular diseases in Solomon Islands.

  28259851   Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI).

  28333262   Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes.

  28552045   Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians.

  29433421   The distribution of three candidate cold-resistant SNPs in six minorities in North China.

  29795460   The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden: the GLACIER Study.

  30157936   FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression.

  31371282   Fish and marine fatty acids intakes, the FADS genotypes and long-term weight gain: a prospective cohort study.

  33177615   Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population.

  35176104   Unveiling forensically relevant biogeographic, phenotype and Y-chromosome SNP variation in Pakistani ethnic groups using a customized hybridisation enrichment forensic intelligence panel.

  35387194   Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.