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SNP information rs498793

RS498793

Normal allele: CC

Fatty acid desaturase gene breakage increases the manifestations of attention-deficit/hyperactivity disorder.

Polymorphism rs498793 is related to topics like this:

Omega 3 genetics

It may seem counterintuitive that substances with the names "fat" and "acid" can be beneficial for...


Research and publications:

  16893529   Association of fatty acid desaturase genes with attention-deficit/hyperactivity disorder.

  20427696   Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.

  20562440   FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.

  20565855   Genetic variation in lipid desaturases and its impact on the development of human disease.

  21414826   Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults.

  23285256   Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism.

  25367143   Effects of FADS and ELOVL polymorphisms on indexes of desaturase and elongase activities: results from a pre-post fish oil supplementation.

  26746237   Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children.

  26912491   Maternal single nucleotide polymorphisms in the fatty acid desaturase 1 and 2 coding regions modify the impact of prenatal supplementation with DHA on birth weight.

  28259851   Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI).

  28552045   Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians.

  28555039   FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.

  28871191   Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects.

  34749668   Effect of n-3 polyunsaturated fatty acids on ischemic heart disease and cardiometabolic risk factors: a two-sample Mendelian randomization study.

CPT2 disease

A condition affecting the oxidation of long-chain fatty acids, Carnitine palmitoyltransferase II...

Nuclear hormone receptors

The activated ligand-regulated transcription factors collectively known as nuclear receptors...

21 hydroxylase

The CYP21A2 gene encodes the human protein, Steroid 21-hydroxylase. This enzyme hydroxylates...

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