SNP information rs737865

Research and publications:

  12802784   A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain

  15098000   COMT haplotypes suggest P2 promoter region relevance for schizophrenia

  15124004   Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families

  15457404   Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

  15505638   Separate and interacting effects within the catechol-O-methyltransferase (COMT) are associated with schizophrenia

  15635644   A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD).

  15931594   An entropy-based statistic for genomewide association studies

  15956988   COMT polymorphisms and anxiety-related personality traits

  16027741   Catechol-O-methyltransferase haplotypes are associated with psychosis in Alzheimer disease

  16214922   Polymorphisms and haplotypes in the cytochrome P450 17A1, prolactin, and catechol-O-methyltransferase genes and non-Hodgkin lymphoma risk.

  16232322   COMT genetic variation confers risk for psychotic and affective disorders: a case control study

  16483362   The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression

  16525418   Association of the Val158Met catechol O-methyltransferase genetic polymorphism with panic disorder.

  16816420   Nonlinear tests for genomewide association studies

  16837108   Haplotypes in cathechol-O-methyltransferase gene confer increased risk for psychosis in Alzheimer disease

  16876132   Catechol-O-methyltransferase (COMT) gene variants predict response to bupropion therapy for tobacco dependence.

  17363961   Clinical involvement of catechol-O-methyltransferase polymorphisms in schizophrenia spectrum disorders: influence on the severity of psychotic symptoms and on the response to neuroleptic treatment

  17427186   Association analysis of COMT polymorphisms and schizophrenia in a Chinese Han population: a case-control study

  17466074   Genetic polymorphisms in dopamine-related genes and smoking cessation in women: a prospective cohort study

  17482701   No associations exist between five functional polymorphisms in the catechol-O-methyltransferase gene and schizophrenia in a Japanese population

  17630406   Dopamine genes and schizophrenia: case closed or evidence pending?

  17707347   Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls

  18081002   Association of catechol-O-methyltransferase variants with loudness dependence of auditory evoked potentials

  18384078   Association study of candidate variants of COMT with neuroticism, anxiety and depression

  18436194   Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes

  18574484   The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase

  18632656   Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms.

  18704099   Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence.

  18715757   Genetic associations with schizophrenia: meta-analyses of 12 candidate genes

  19071221   Impact of interacting functional variants in COMT on regional gray matter volume in human brain.

  19077118   Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia.

  19290789   Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment.

  19329282   Meta-analysis of association between genetic variants in COMT and schizophrenia: an update.

  19365560   Low enzymatic activity haplotypes of the human catechol-O-methyltransferase gene: enrichment for marker SNPs.

  19721400   Association between COMT gene and Chinese male schizophrenic patients with violent behavior.

  19911060   Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.

  19997043   Variation in the catechol-O-methyltransferase Val 158 Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents.

  20083391   A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry.

  20157235   Genetics of psychosis in Alzheimer's disease: a review.

  20531207   The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: a case-control association study.

  20667552   Catechol-o-methyltransferase gene modulation on suicidal behavior and personality traits: review, meta-analysis and association study.

  21119772   A Hybrid Machine Learning Method for Fusing fMRI and Genetic Data: Combining both Improves Classification of Schizophrenia.

  21172166   Pharmacogenetics of antidepressant response.

  21204206   Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population

  21217836   No Association Between Functional Polymorphisms in COMT and MTHFR and Schizophrenia Risk in Korean Population.

  21462137   [An association study of COMT gene polymorphisms with schizophrenia].

  21600957   COMT and age at onset in mood disorders: a replication and extension study.

  21656904   Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.

  21658613   Host genetics in follicular lymphoma.

  21940152   The impact of COMT gene polymorphisms on suicidality in treatment resistant major depressive disorder--a European multicenter study.

  22650965   Paradox of schizophrenia genetics: is a paradigm shift occurring?

  22705295   Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort.

  22856873   Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects.

  23178897   The catechol-O-methyltransferase gene (COMT) and cognitive function from childhood through adolescence.

  23209597   Investigating the genetic basis of theory of mind (ToM): the role of catechol-O-methyltransferase (COMT) gene polymorphisms.

  23351565   Potential role of membrane-bound COMT gene polymorphisms in female depression vulnerability.

  23598060   Association study of polymorphisms in the alpha 7 nicotinic acetylcholine receptor subunit and catechol-o-methyl transferase genes with sensory gating in first-episode schizophrenia.

  23762769   Frequency Distribution of COMT Polymorphisms in Greek Patients with Schizophrenia and Controls: A Study of SNPs rs737865, rs4680, and rs165599.

  23963787   Complex multilocus effects of catechol-O-methyltransferase haplotypes predict pain and pain interference 6 weeks after motor vehicle collision.

  24205329   Detection of regulatory SNPs in human genome using ChIP-seq ENCODE data.

  24782743   Association of COMT and COMT-DRD2 interaction with creative potential.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  24990354   Variants in maternal COMT and MTHFR genes and risk of neural tube defects in offspring.

  25159270   Interactions between catechol-O-methyltransferase genotype, parenting, and gender predict childhood internalizing symptoms and inhibitory control: Evidence for differential susceptibility.

  25218601   Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain.

  25320962   COMT haplotypes modulate associations of antenatal maternal anxiety and neonatal cortical morphology.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  26858644   Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling.

  26920810   Modulative effects of COMT haplotype on age-related associations with brain morphology.

  26954460   COMT genotype is associated with differential expression of muscarinic M1 receptors in human cortex.

  26974654   Serotonin and Dopamine Gene Variation and Theory of Mind Decoding Accuracy in Major Depression: A Preliminary Investigation.

  27166759   Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.

  27459874   Evaluation of the iPLEX® ADME PGx Pro Panel and allele frequencies of pharmacogenetic markers in Danes.

  27636225   An Expert Review of Pharmacogenomics of Sickle Cell Disease Therapeutics: Not Yet Ready for Global Precision Medicine.

  28142104   A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity.

  28273278   Catechol-O-methyltransferase (COMT) polymorphisms modulate working memory in individuals with schizophrenia and healthy controls.

  28746172   A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers.

  28822116   Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

  29330410   The Impact of COMT and Childhood Maltreatment on Suicidal Behaviour in Affective Disorders.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30218069   Catechol-O-methyltransferase (COMT) genotypes are associated with varying soluble, but not membrane-bound COMT protein in the human prefrontal cortex.

  30692067   [Postpartum depression: association with genetic polymorphisms of noradrenaline metabolic enzymes and the risk factors].

  30706571   A candidate gene study of dementia risk in older postmenopausal women: Results from the Women's Health Initiative Memory Study.

  32985495   Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

  35211407   The COMT Genetic Factor Regulates Chemotherapy-Related Prospective Memory Impairment in Survivors With HER2-/+ Breast Cancer.

  35285297   HUMAN STUDY COMT and DRD3 haplotype-associated pain intensity and acute care utilization in adult sickle cell disease.

  35968333   COMT rs737865 mediates chemobrain in breast cancer patients with various levels of Ki-67.