Normal allele: GG
Variants in the tryptophan hydroxylase gene involved in the development and treatment of opiate, heroin and cocaine addiction.
Polymorphism rs1799913 is related to topics like this:
Research and publications:
18181017 TPH2 and TPH1: association of variants and interactions with heroin addiction.
21073637 Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.
21333900 The role of genetics in IBS
22650965 Paradox of schizophrenia genetics: is a paradigm shift occurring?
22933845 Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse.
27573591 Personality traits as an endophenotype in genetic studies on suicidality in bipolar disorder.
27895608 Genetic Consideration of Schizotypal Traits: A Review.
30789538 Association of polymorphisms in HTR2A, TPH1, and TPH2 genes with attempted suicide in rural China.
31817010 Variation of Genes Encoding Tryptophan Catabolites Pathway Enzymes in Stroke.
35040003 Identification of putative genetic variants in major depressive disorder patients in Pakistan.