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SNP information rs6296


Normal allele: CC

Polymorphism rs6296 is related to topics like this:

Serotonin transporter sert

In humans, the SLC6A4 gene encodes a protein referred to as both the sodium-dependent serotonin...

Is OCD obsessive compulsive disorder genetic

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by features known as...

ADHD is it genetic

ADHD, a behavioral disorder that usually commences during childhood, is marked by a brief attention...

Research and publications:

  15206000   Transmission disequilibrium studies in children and adolescents with obsessive-compulsive disorders pertaining to polymorphisms of genes of the serotonergic pathway.

  16380908   Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder

  17948897   Association of 5-HT1B receptor polymorphisms with the loudness dependence of auditory evoked potentials in a community-based sample of healthy volunteers.

  18698231   Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.

  19350534   Functional polymorphisms in the serotonin 1B receptor gene (HTR1B) predict self-reported anger and hostility among young men.

  19379518   Development of a fingerprinting panel using medically relevant polymorphisms.

  19721846   Candidate genes involved in neural plasticity and the risk for attention-deficit hyperactivity disorder: a meta-analysis of 8 common variants

  20201854   Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.

  20388441   [Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis].

  20565774   Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project

  20638825   The HTR1A and HTR1B receptor genes influence stress-related information processing.

  20732623   Measured gene-by-environment interaction in relation to attention-deficit/hyperactivity disorder.

  20732627   Case-control genome-wide association study of attention-deficit/hyperactivity disorder.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21937687   Influence and interaction of genetic polymorphisms in the serotonin system and life stress on antidepressant drug response.

  22005095   A haplotype analysis is consistent with the role of functional HTR1B variants in alcohol dependence.

  22024213   A novel gene-environment interaction involved in endometriosis

  22106445   HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genes.

  22735397   Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner.

  22841130   Shared and unique genetic contributions to attention deficit/hyperactivity disorder and substance use disorders: a pilot study of six candidate genes.

  22933845   Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse.

  22945537   Serotonin receptor 1B genotype and hostility, anger and aggressive behavior through the lifespan: the Young Finns study.

  22957248   Genetics of temporal lobe epilepsy: a review.

  23375453   Genetic association of 5-HT1A and 5-HT1B gene polymorphisms with migraine in a Turkish population.

  23808549   Candidate gene associations with withdrawn behavior.

  24596569   Gene-environment interactions and intermediate phenotypes: early trauma and depression.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  25652393   Interaction between 5-HTTLPR and 5-HT1B genotype status enhances cerebral 5-HT1A receptor binding.

  25658328   Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits.

  26123080   Association between the polymorphism of C861G (rs6296) in the serotonin 1B receptor gene and Tourette syndrome in Han Chinese people.

  26227246   Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry.

  26428549   Variation in serotonin neurotransmission genes affects neural activation during response inhibition in adolescents and young adults with ADHD and healthy controls.

  26505676   Association between genetic variants of serotonergic and glutamatergic pathways and the concentration of neurometabolites of the anterior cingulate cortex in paediatric patients with obsessive-compulsive disorder.

  27230021   Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traits.

  27445670   5-HT2A Gene Variants Moderate the Association between PTSD and Reduced Default Mode Network Connectivity.

  27529241   The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key?

  27721799   Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.

  28007644   Association between HTR1B alleles and suicidal ideation in individuals with major depressive disorder.

  28282362   Gene-to-gene interactions regulate endogenous pain modulation in fibromyalgia patients and healthy controls-antagonistic effects between opioid and serotonin-related genes.

  28512748   Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability.

  28639488   Prenatal exposure to serotonin reuptake inhibitors and congenital heart anomalies: an exploratory pharmacogenetics study.

  28923721   Evidence of sexual dimorphism of HTR1B gene on major adult ADHD comorbidities.

  29275155   HTR1A/1B DNA methylation may predict escitalopram treatment response in depressed Chinese Han patients.

  29709878   Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis.

  30074224   Association of Serotonin Receptors with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis.

  30700110   Genetic Variants and the Cortisol Response in Children: An Exploratory Study.

  31510870   There is no association between rs6296 and alcoholism: a meta-analysis.

  32576619   Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders.

  33096746   Genetic Landscape of Common Epilepsies: Advancing towards Precision in Treatment.

  33244961   [The role of genetic factors in the development of suicidal behavior in individuals with dependence on synthetic cathinones].

  34575611   Association of postoperative pain and PONV after minimally invasive surgery with serotonin concentration and polymorphism of receptor genes.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

  35438303   Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.

  35776190   Correction to: Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.

  35893072   Are Pain Polymorphisms Associated with the Risk and Phenotype of Post-COVID Pain in Previously Hospitalized COVID-19 Survivors?

CYP21 deficiency

The inability to synthesize cortisol, known as congenital adrenal hyperplasia (CAH), is responsible...

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...

Mitochondria dna

The mitochondria contain circular chromosomes known as mitochondrial DNA and are organelles...