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SNP information rs6313


Normal allele: GG

TPH-2 polymorphisms affect response to treatment with antidepressants and SSRIs.

Polymorphism rs6313 is related to topics like this:

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Research and publications:

  15882913   The KPNA3 gene may be a susceptibility candidate for schizophrenia.

  16272956   CYP2A6, MAOA, DBH, DRD4, and 5HT2A genotypes, smoking behaviour and cotinine levels in 1518 UK adolescents.

  16642436   Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.

  17000047   Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder.

  17440930   Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.

  17521439   Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.

  17590256   5-HT2A SNPs and the Temperament and Character Inventory.

  17601350   A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

  17964050   Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients.

  18006541   Genetic variations in the serotonin 5-HT2A receptor gene (HTR2A) are associated with rheumatoid arthritis.

  18191318   Association study between obsessive-compulsive disorder and serotonergic candidate genes.

  18196244   Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility

  18712714   Genetic variation in the serotonin 2A receptor and suicidal ideation in a sample of 270 Irish high-density schizophrenia families.

  18797395   Association between the A-1438G polymorphism of the serotonin 2A receptor gene and nonimpulsive suicide attempts.

  18801406   Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression.

  19156168   Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

  19184136   Examination of association of genes in the serotonin system to autism

  19197363   A genome-wide investigation of SNPs and CNVs in schizophrenia.

  19379518   Development of a fingerprinting panel using medically relevant polymorphisms.

  19387614   HTR2A A-1438G/T102C polymorphisms predict negative symptoms performance upon aripiprazole treatment in schizophrenic patients.

  19475583   A candidate gene study of Tardive dyskinesia in the CATIE schizophrenia trial.

  19545856   Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study.

  19590397   5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

  19647026   Analysis of serotonin receptor 2A gene (HTR2A): association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes.

  19693267   Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

  19742166   Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features.

  19897250   An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population.

  19924111   Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.

  19937159   HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20157235   Genetics of psychosis in Alzheimer's disease: a review.

  20373668   Psychiatric pharmacogenomic testing in clinical practice.

  20403506   Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.

  20431430   The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness.

  20565774   Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project

  20633049   Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

  20827275   Influence of HTR2A polymorphisms and parental rearing on personality traits in healthy Japanese subjects.

  21049304   Influence of candidate genes on attention problems in children: a longitudinal study.

  21136126   Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression.

  21162693   Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.

  21172166   Pharmacogenetics of antidepressant response.

  21320838   Variations in 5-HT2A influence spatial cognitive abilities and working memory.

  21333900   The role of genetics in IBS

  21621273   Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: a preliminary report.

  21687501   Pharmacogenetics of antidepressants.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21728034   Methamphetamine-associated psychosis.

  21905019   Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia.

  21930285   The CC genotype in HTR2A T102C polymorphism is associated with behavioral impulsivity in alcohol-dependent patients.

  21966275   Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

  21969281   Influence of birth weight on internalizing traits modulated by serotonergic genes.

  22024213   A novel gene-environment interaction involved in endometriosis

  22074755   Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study.

  22214315   Isochromosome 13 in a patient with childhood-onset schizophrenia, ADHD, and motor tic disorder.

  22545912   Association of genetic, psychological and behavioral factors with sleep bruxism in a Japanese population.

  22735397   Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner.

  22751492   Family-based study of HTR2A in suicide attempts: observed gene, gene × environment and parent-of-origin associations.

  22893819   Stress, vulnerability and resilience, a developmental approach.

  22933845   Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse.

  23245538   Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine.

  23321485   The CC genotype in the T102C HTR2A polymorphism predicts relapse in individuals after alcohol treatment.

  23397970   Interpersonal and genetic origins of adult attachment styles: a longitudinal study from infancy to early adulthood.

  23429840   Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease.

  23499153   Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintenance of pregnancy.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  24178752   Association of the HTR2A gene with alcohol and heroin abuse.

  24491308   Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men.

  24801750   Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25108775   Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis.

  25111588   Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women.

  25174699   Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain.

  25223859   Serotonin risk factors for the development of hypertension in pregnancy.

  25658328   Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits.

  25733959   Pharmacogenetics and outcome with antipsychotic drugs.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  26261165   Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study.

  26322220   A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.

  26390831   Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways.

  26544898   The impact of serotonin receptor 1A and 2A gene polymorphisms and interactions on suicide attempt and suicide risk in depressed patients with insufficient response to treatment--a European multicentre study.

  26616111   Disorder-specific genetic factors in obsessive-compulsive disorder: A comprehensive meta-analysis.

  26764241   Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach.

  26812280   Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia.

  26989097   Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.

  27091189   Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway.

  27161551   Emotion moderates the association between HTR2A (rs6313) genotype and antisaccade latency.

  27217270   Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis.

  27325396   The Ser9Gly variant of the dopamine D3 receptor is associated with impulse control disorders in patients with Parkinson's disease.

  27375535   Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review.

  27399274   Alcohol misuse in emerging adulthood: Association of dopamine and serotonin receptor genes with impulsivity-related cognition.

  27445478   5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients.

  27445670   5-HT2A Gene Variants Moderate the Association between PTSD and Reduced Default Mode Network Connectivity.

  27489378   Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population.

  27521242   TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs.

  27529241   The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key?

  27598719   Meta-analysis of polymorphism rs6311 and rs6313 in the 5-HT(2A)R gene and schizophrenia.

  27611726   Genetic polymorphisms in the serotonergic system are associated with circadian manifestations of bruxism.

  27721799   Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.

  27756686   Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population.

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