Normal allele: GG
TPH-2 polymorphisms affect response to treatment with antidepressants and SSRIs.
Polymorphism rs6313 is related to topics like this:
Research and publications:
15882913 The KPNA3 gene may be a susceptibility candidate for schizophrenia.
17590256 5-HT2A SNPs and the Temperament and Character Inventory.
18191318 Association study between obsessive-compulsive disorder and serotonergic candidate genes.
19156168 Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.
19184136 Examination of association of genes in the serotonin system to autism
19197363 A genome-wide investigation of SNPs and CNVs in schizophrenia.
19379518 Development of a fingerprinting panel using medically relevant polymorphisms.
19475583 A candidate gene study of Tardive dyskinesia in the CATIE schizophrenia trial.
19590397 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.
19937159 HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.
20157235 Genetics of psychosis in Alzheimer's disease: a review.
20373668 Psychiatric pharmacogenomic testing in clinical practice.
20633049 Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?
21049304 Influence of candidate genes on attention problems in children: a longitudinal study.
21136126 Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression.
21162693 Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.
21172166 Pharmacogenetics of antidepressant response.
21320838 Variations in 5-HT2A influence spatial cognitive abilities and working memory.
21333900 The role of genetics in IBS
21687501 Pharmacogenetics of antidepressants.
21728034 Methamphetamine-associated psychosis.
21966275 Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
21969281 Influence of birth weight on internalizing traits modulated by serotonergic genes.
22024213 A novel gene-environment interaction involved in endometriosis
22214315 Isochromosome 13 in a patient with childhood-onset schizophrenia, ADHD, and motor tic disorder.
22735397 Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner.
22893819 Stress, vulnerability and resilience, a developmental approach.
22933845 Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse.
23429840 Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease.
23733030 Pharmacogenetics in major depression: a comprehensive meta-analysis.
24178752 Association of the HTR2A gene with alcohol and heroin abuse.
24944790 Screening for 392 polymorphisms in 141 pharmacogenes.
25223859 Serotonin risk factors for the development of hypertension in pregnancy.
25733959 Pharmacogenetics and outcome with antipsychotic drugs.
26322220 A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.
26390831 Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways.
26616111 Disorder-specific genetic factors in obsessive-compulsive disorder: A comprehensive meta-analysis.
27161551 Emotion moderates the association between HTR2A (rs6313) genotype and antisaccade latency.
27598719 Meta-analysis of polymorphism rs6311 and rs6313 in the 5-HT(2A)R gene and schizophrenia.