SNP information rs6311

Research and publications:

  16642436   Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.

  16814396   Anger- and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene.

  16876316   Association study of genetic risk factors for sporadic Parkinson's disease in patients from Russia using APEX technology.

  17241828   Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorder.

  17440930   Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.

  17590256   5-HT2A SNPs and the Temperament and Character Inventory.

  17688403   Association of serotonin 2A receptor and lack of association of CYP1A2 gene polymorphism with tardive dyskinesia in a Turkish population.

  18006541   Genetic variations in the serotonin 5-HT2A receptor gene (HTR2A) are associated with rheumatoid arthritis.

  18079067   Genetic evaluation of the serotonergic system in chronic fatigue syndrome.

  18081710   Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.

  18191318   Association study between obsessive-compulsive disorder and serotonergic candidate genes.

  18196244   Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility

  18439448   Stress, genes and the biology of suicidal behavior.

  18797395   Association between the A-1438G polymorphism of the serotonin 2A receptor gene and nonimpulsive suicide attempts.

  18826444   Serotonergic genes and amygdala activity in response to negative affective facial stimuli in Korean women.

  19328219   Differential role of serotonergic polymorphisms in alcohol and heroin dependence.

  19359258   Cohort profile: risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project.

  19545856   Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study.

  19560507   Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder.

  19590397   5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

  19647026   Analysis of serotonin receptor 2A gene (HTR2A): association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes.

  19690620   Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes.

  19911060   Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.

  19937159   HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20191112   The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.

  20198576   Association between the -1438A/G polymorphism of the serotonin 2A receptor gene and late-onset psoriasis in a Thai population.

  20421848   Interactions between functional serotonergic polymorphisms and demographic factors influence personality traits in healthy Spanish Caucasians.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20580209   Seasonality and winter-type seasonal depression are associated with the rs731779 polymorphism of the serotonin-2A receptor gene.

  20633049   Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

  20827275   Influence of HTR2A polymorphisms and parental rearing on personality traits in healthy Japanese subjects.

  20941551   Functional genomics of serotonin receptor 2A (HTR2A): interaction of polymorphism, methylation, expression and disease association.

  21049304   Influence of candidate genes on attention problems in children: a longitudinal study.

  21136126   Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression.

  21162693   Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.

  21172166   Pharmacogenetics of antidepressant response.

  21333900   The role of genetics in IBS

  21687501   Pharmacogenetics of antidepressants.

  21711518   Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

  21728034   Methamphetamine-associated psychosis.

  21741447   Interaction between two HTR2A polymorphisms and gender is associated with treatment response in MDD.

  21760883   Genetic determinants of UV-susceptibility in non-melanoma skin cancer.

  21874579   Pilot study on HTR2A promoter polymorphism, -1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive-compulsive disorder.

  22046326   "Smoking genes": a genetic association study.

  22214315   Isochromosome 13 in a patient with childhood-onset schizophrenia, ADHD, and motor tic disorder.

  22615781   Candidate gene-based association study of antipsychotic-induced movement disorders in long-stay psychiatric patients: a prospective study.

  22650965   Paradox of schizophrenia genetics: is a paradigm shift occurring?

  22717018   Escitalopram reduces attentional performance in anxious older adults with high-expression genetic variants at serotonin 2A and 1B receptors.

  22933845   Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse.

  23158458   Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.

  23221997   TPH1, MAOA, serotonin receptor 2A and 2C genes in citalopram response: possible effect in melancholic and psychotic depression.

  23318131   Association of serotonin-1A and -2A receptor promoter polymorphisms with depressive symptoms, functional recovery, and pain in patients 6 months after lumbar disc surgery.

  23429840   Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease.

  23547754   Genetics of serotonin receptors and depression: state of the art.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  23872233   The relationship between the presence of ADHD and certain candidate gene polymorphisms in a Turkish sample.

  24021217   Common selective serotonin reuptake inhibitor side effects in older adults associated with genetic polymorphisms in the serotonin transporter and receptors: data from a randomized controlled trial.

  24178752   Association of the HTR2A gene with alcohol and heroin abuse.

  24307977   A pilot study evaluating genetic and environmental factors for postpartum depression.

  24355137   The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and borderline personality disorder in female heroin-dependent Chinese subjects.

  24533444   Female sexual dysfunction in patients with major depressive disorder (MDD) treated with selective serotonin reuptake inhibitor (SSRI) and its association with serotonin 2A-1438 G/A single nucleotide polymorphisms.

  24643765   5-HTTLPR, HTR1A, and HTR2A cumulative genetic score interacts with mood reactivity to predict mood-congruent gaze bias.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  24885933   Towards the clinical implementation of pharmacogenetics in bipolar disorder.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25017045   The neurobiological link between OCD and ADHD.

  25041420   Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain.

  25108775   Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis.

  25174699   Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain.

  25264393   Association between serotonin cumulative genetic score and the Behavioral Approach System (BAS): Moderation by early life environment.

  25459290   Single 5HTR2A-1438 A/G nucleotide polymorphism affects performance in a metacontrast masking task: implications for vulnerability testing and neuromodulation of pyramidal cells.

  25658328   Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits.

  26149086   DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects.

  26261165   Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study.

  26322220   A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.

  26543368   Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.

  26613086   Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

  26616111   Disorder-specific genetic factors in obsessive-compulsive disorder: A comprehensive meta-analysis.

  26858594   Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits.

  26989097   Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.

  27091189   Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway.

  27126880   Serotonin as a New Therapeutic Target for Diabetes Mellitus and Obesity.

  27193909   Gender Interacts with Opioid Receptor Polymorphism A118G and Serotonin Receptor Polymorphism -1438 A/G on Speed-Dating Success.

  27247849   Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

  27375535   Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review.

  27445478   5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients.

  27445670   5-HT2A Gene Variants Moderate the Association between PTSD and Reduced Default Mode Network Connectivity.

  27489378   Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population.

  27521242   TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs.

  27529241   The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key?

  27598719   Meta-analysis of polymorphism rs6311 and rs6313 in the 5-HT(2A)R gene and schizophrenia.

  27721799   Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.

  27756686   Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population.

  27757066   Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.

  27895608   Genetic Consideration of Schizotypal Traits: A Review.

  27912162   Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans.

  28103253   Polymorphisms in HTR2A and DRD4 Predispose to Smoking and Smoking Quantity.

  28470827   Pharmacogenomics and Efficacy of Risperidone Long-Term Treatment in Thai Autistic Children and Adolescents.

  28576508   A review of the role of serotonin system genes in obsessive-compulsive disorder.