SNP information rs7997012

Research and publications:

  16642436   Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.

  17671280   Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort.

  18803430   Pharmacogenetics of major depression: insights from level 1 of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial.

  19077664   Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response.

  19095219   Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder.

  19381154   Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene-environment study.

  19428704   Genetic association analysis of serotonin 2A receptor gene (HTR2A) with bipolar disorder and major depressive disorder in the Japanese population.

  19590397   5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

  19636338   Pharmacogenetics and olanzapine treatment: CYP1A2*1F and serotonergic polymorphisms influence therapeutic outcome.

  19758789   HTR2A gene variation is involved in antidepressant treatment response.

  19924111   Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.

  19937159   HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.

  20047709   Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB.

  20194481   Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder.

  20373668   Psychiatric pharmacogenomic testing in clinical practice.

  20453658   5HT1A and 5HT2A receptor genes in treatment response phenotypes in major depressive disorder.

  21136126   Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression.

  21172166   Pharmacogenetics of antidepressant response.

  21741447   Interaction between two HTR2A polymorphisms and gender is associated with treatment response in MDD.

  22006095   Serotonin receptor 2A (HTR2A) gene polymorphism predicts treatment response to venlafaxine XR in generalized anxiety disorder.

  22738351   Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response.

  22907732   Interaction between polymorphisms in serotonin transporter (SLC6A4) and serotonin receptor 2A (HTR2A) genes predict treatment response to venlafaxine XR in generalized anxiety disorder.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  23537781   Variation in the HTR1A and HTR2A genes and social adjustment in depressed patients.

  23733030   Pharmacogenetics in major depression: a comprehensive meta-analysis.

  23759279   HTR2A gene-child abuse interaction and association with a history of suicide attempt among Caucasian depressed psychiatric inpatients.

  24128936   PharmGKB summary: venlafaxine pathway.

  24192302   Polymorphisms in serotonergic pathways influence the outcome of antidepressant therapy in psychiatric inpatients.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  24885933   Towards the clinical implementation of pharmacogenetics in bipolar disorder.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25108775   Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis.

  26262902   Pharmacogenetic Study of Serotonin Transporter and 5HT2A Genotypes in Autism.

  26544898   The impact of serotonin receptor 1A and 2A gene polymorphisms and interactions on suicide attempt and suicide risk in depressed patients with insufficient response to treatment--a European multicentre study.

  26989097   Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.

  27294413   Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.

  27445478   5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients.

  27445670   5-HT2A Gene Variants Moderate the Association between PTSD and Reduced Default Mode Network Connectivity.

  27521242   TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs.

  27529241   The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key?

  27721799   Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions.

  27757066   Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.

  29975559   Further Support for the Involvement of Genetic Variants Related to the Serotonergic Pathway in the Antidepressant Response in Children and Adolescents After a 12-Month Follow-Up: Impact of the HTR2A rs7997012 Polymorphism.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30178121   Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample.

  31019472   The Interaction of TPH2 and 5-HT2A Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study.

  31721892   Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial.

  32697408   Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels.

  32819202   Association between genetic polymorphism and antidepressants in major depression: a network meta-analysis.

  33097827   Associations between the 1438A/G, 102T/C, and rs7997012G/A polymorphisms of HTR2A and the safety and efficacy of antidepressants in depression: a meta-analysis.

  34385834   Individualized drug selection by assessing drug properties, pharmacogenomics, and clinical parameters: effectiveness of a bioinformatics tool compared to a clinically established counseling process.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.