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SNP information rs6314


Normal allele: GG

The serotonin receptor gene HTR2A polymorphism is associated with bipolar affective disorder and autism spectrum disorder.

Polymorphism rs6314 is related to topics like this:

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Research and publications:

  16380908   Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder

  16642433   Polymorphism in maternal LRP8 gene is associated with fetal growth

  17000047   Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder.

  17601350   A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

  18006541   Genetic variations in the serotonin 5-HT2A receptor gene (HTR2A) are associated with rheumatoid arthritis.

  18081710   Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.

  18611292   The His452Tyr variant of the gene encoding the 5-HT2A receptor is specifically associated with consolidation of episodic memory in humans.

  18712714   Genetic variation in the serotonin 2A receptor and suicidal ideation in a sample of 270 Irish high-density schizophrenia families.

  19077664   Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response.

  19359258   Cohort profile: risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project.

  19584773   Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort.

  19647026   Analysis of serotonin receptor 2A gene (HTR2A): association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes.

  19734545   A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

  20008943   Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study.

  20047709   Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB.

  20125193   Common genetic variation and performance on standardized cognitive tests.

  20452482   Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

  20633049   Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

  21049304   Influence of candidate genes on attention problems in children: a longitudinal study.

  21172166   Pharmacogenetics of antidepressant response.

  21333900   The role of genetics in IBS

  21687501   Pharmacogenetics of antidepressants.

  22105624   The genetics of attention deficit/hyperactivity disorder in adults, a review.

  22615781   Candidate gene-based association study of antipsychotic-induced movement disorders in long-stay psychiatric patients: a prospective study.

  23544600   Two functional serotonin polymorphisms moderate the effect of food reinforcement on BMI.

  23808549   Candidate gene associations with withdrawn behavior.

  24200957   Irritable bowel syndrome-diarrhea: characterization of genotype by exome sequencing, and phenotypes of bile acid synthesis and colonic transit.

  24307977   A pilot study evaluating genetic and environmental factors for postpartum depression.

  24801750   Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  24958631   Serotonin transporter gene: a new polymorphism may affect response to antidepressant treatments in major depressive disorder.

  25563748   Variation in Dopamine D2 and Serotonin 5-HT2A Receptor Genes is Associated with Working Memory Processing and Response to Treatment with Antipsychotics.

  25658328   Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits.

  25733959   Pharmacogenetics and outcome with antipsychotic drugs.

  25912540   Effect of polymorphisms of three genes mediating monoamine signalling on brain morphometry in schizophrenia and healthy subjects.

  26322220   A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.

  26543368   Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.

  26764241   Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach.

  26989097   Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.

  27217270   Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis.

  27489378   Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population.

  27529241   The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key?

  27757066   Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.

  27846195   Genome-wide association study of paliperidone efficacy.

  27853387   Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics.

  28054990   mRNA Expression and DNA Methylation Analysis of Serotonin Receptor 2A (HTR2A) in the Human Schizophrenic Brain.

  29526601   Association between serotonin 2A receptor genetic variations, stressful life events and suicide.

  29529493   Does the serotonin receptor gene (rs6313 and rs6314) polymorphism have a role in suicidal attempts?

  30137607   Translational genomic research: the role of genetic polymorphisms in MBSR program among breast cancer survivors (MBSR[BC]).

  30178121   Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample.

  30607769   Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population.

  30883267   A systematic review of genome-wide association studies of antipsychotic response.

  32086104   Association of Genetic Variants of Dopamine and Serotonin In Schizophrenia.

  32697408   Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels.

  32819202   Association between genetic polymorphism and antidepressants in major depression: a network meta-analysis.

  33096746   Genetic Landscape of Common Epilepsies: Advancing towards Precision in Treatment.

  33278020   Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics.

  34385834   Individualized drug selection by assessing drug properties, pharmacogenomics, and clinical parameters: effectiveness of a bioinformatics tool compared to a clinically established counseling process.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

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