Normal allele: GG
Tendency to higher nicotine dependence, increased impulsivity and thrill-seeking.
Polymorphism rs4648317 is related to topics like this:
Research and publications:
19512960 Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.
21514569 The AVPR1A gene and substance use disorders: association, replication, and functional evidence.
21906503 Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.
22244514 Sensorimotor gating and D2 receptor signalling: evidence from a molecular genetic approach.
22963930 Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.
24618367 Aggression, DRD1 polymorphism, and lesion location in penetrating traumatic brain injury.
24782743 Association of COMT and COMT-DRD2 interaction with creative potential.
24844177 Genetic risk prediction and neurobiological understanding of alcoholism.
25955176 Polymorphic variants in the dopamine receptor D2 in women with endometriosis-related infertility.
27247849 Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.
27933030 The Association of DRD2 with Insight Problem Solving.
30093869 Biological Predictors of Clozapine Response: A Systematic Review.
31129315 Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.