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SNP information rs4648317

RS4648317

Normal allele: GG

Tendency to higher nicotine dependence, increased impulsivity and thrill-seeking.

Polymorphism rs4648317 is related to topics like this:

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Research and publications:

  18077373   Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

  18434921   Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence.

  19373123   Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution.

  19512960   Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.

  19968402   Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.

  21514569   The AVPR1A gene and substance use disorders: association, replication, and functional evidence.

  21906503   Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.

  21948099   Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?

  22244514   Sensorimotor gating and D2 receptor signalling: evidence from a molecular genetic approach.

  22424959   DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience.

  22963930   Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.

  24618367   Aggression, DRD1 polymorphism, and lesion location in penetrating traumatic brain injury.

  24782743   Association of COMT and COMT-DRD2 interaction with creative potential.

  24844177   Genetic risk prediction and neurobiological understanding of alcoholism.

  25955176   Polymorphic variants in the dopamine receptor D2 in women with endometriosis-related infertility.

  27247849   Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

  27933030   The Association of DRD2 with Insight Problem Solving.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  31129315   Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain.

  31867628   Genetic and Epigenetic Analysis Revealing Variants in the NCAM1-TTC12-ANKK1-DRD2 Cluster Associated Significantly With Nicotine Dependence in Chinese Han Smokers.

  31933869   Functional tag SNPs inside the DRD2 gene as a genetic risk factor for major depressive disorder in the Chinese Han population.

  33043160   Association of DRD2 gene polymorphisms with schizophrenia in the young Bangladeshi population: A pilot study.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

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