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SNP information rs4532

Normal allele: TT

Affects dopamine D1 receptors associated with autism spectrum disorders.

Polymorphism rs4532 is related to topics like this:

DNA test for autism

We recommend that anyone who has been diagnosed with autism undergo genetic testing. Unfortunately,...

The membrane-bound protein called the dopamine transporter (DAT), also known as the...


Research and publications:

  15087492   A new approach to SNP genotyping with fluorescently labeled mononucleotides.

  17092969   Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.

  18092181   Significant association of DRD1 with nicotine dependence.

  18205172   A DRD1 haplotype is associated with risk for autism spectrum disorders in male-only affected sib-pair families.

  18341651   A haplotype of the DRD1 gene is associated with alcohol dependence.

  18366720   Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.

  18821566   SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.

  20382433   No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia.

  20456319   Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia.

  20592018   D1 and D2 dopamine receptor-mediated inhibition of activated normal T cell proliferation is lost in jurkat T leukemic cells.

  21178390   Associations between DRDs and schizophrenia in a Korean population: multi-stage association analyses.

  21181138   Analysis of genetic variations in the dopamine D1 receptor (DRD1) gene and antipsychotics-induced tardive dyskinesia in schizophrenia.

  21527290   Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.

  21728034   Methamphetamine-associated psychosis.

  21955727   An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.

  22559203   DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families.

  22719919   Glutamate and synaptic plasticity systems and smoking behavior: results from a genetic association study.

  22806211   The genetics of addiction-a translational perspective.

  23036699   DRD1 rs4532 polymorphism: a potential pharmacogenomic marker for treatment response to antipsychotic drugs.

  23044706   Dopamine receptor D1 and postsynaptic density gene variants associate with opiate abuse and striatal expression levels.

  24410775   Moderator effects of working memory on the stability of ADHD symptoms by dopamine receptor gene polymorphisms during development.

  24790447   Genetic association between the dopamine D1-receptor gene and paranoid schizophrenia in a northern Han Chinese population.

  25179995   Association of dopamine receptor D1 (DRD1) polymorphisms with risperidone treatment response in Chinese schizophrenia patients.

  25324626   Research in China on the molecular genetics of schizophrenia.

  25658328   Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits.

  25660313   Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and the risk for alcohol dependence.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  26213377   Meta-analysis of dopamine receptor D1 rs4532 polymorphism and susceptibility to antipsychotic treatment response.

  26429319   Influence of dopamine receptor gene polymorphisms on circulating T lymphocytes: A pilot study in healthy subjects.

  26730182   Association between GRK4 and DRD1 gene polymorphisms and hypertension: a meta-analysis.

  27647283   Dopamine Receptor Genes Modulate Associative Memory in Old Age.

  27895608   Genetic Consideration of Schizotypal Traits: A Review.

  28041918   Prediction of functional outcome in young patients with a recent-onset psychiatric disorder: Beyond the traditional diagnostic classification system.

  28940477   cAMP levels in lymphocytes and CD4(+) regulatory T-cell functions are affected by dopamine receptor gene polymorphisms.

  29623639   Pharmacogenetics of Opioid Use Disorder Treatment.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30103286   Association between dopamine receptor gene polymorphisms and effects of risperidone treatment: A systematic review and meta-analysis.

  30607769   Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population.

  30967134   A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia.

  31123756   The Role of DRD1 and DRD2 Receptors for Response Selection Under Varying Complexity Levels: Implications for Metacontrol Processes.

  31289926   Divergence of an association between depressive symptoms and a dopamine polygenic score in Caucasians and Asians.

  31559529   Influence of dopamine-related genes on craving, impulsivity, and aggressiveness in Korean males with alcohol use disorder.

  31610297   Dopamine D1, but not D2, signaling protects mental representations from distracting bottom-up influences.

  34276537   Potential Prognostic Impact of Dopamine Receptor D1 (rs4532) Polymorphism in Post-stroke Outcome in the Elderly.

  34440083   Candidate Genes Encoding Dopamine Receptors as Predictors of the Risk of Antipsychotic-Induced Parkinsonism and Tardive Dyskinesia in Schizophrenic Patients.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

  35666584   Genetic associations with technical capabilities in English academy football players: a preliminary study.

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