SNP information rs1800497

Research and publications:

  1969501   Allelic association of human dopamine D2 receptor gene in alcoholism.

  9429233   D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele.

  9650634   The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes.

  10395223   Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers.

  11105655   Reward deficiency syndrome: genetic aspects of behavioral disorders.

  15146457   Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1.

  15370155   The genetic basis for smoking behavior: a systematic review and meta-analysis.

  15479180   Progress in searching for susceptibility loci and genes for smoking-related behaviour.

  15492764   Dopamine receptor DRD2 genotype and smoking cessation outcome following treatment with bupropion SR.

  16380908   Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder

  17135598   No evidence for a major role of polymorphisms during bupropion treatment.

  17417059   A dopamine D2 receptor gene-related polymorphism is associated with schizophrenia in a Spanish population isolate.

  17466074   Genetic polymorphisms in dopamine-related genes and smoking cessation in women: a prospective cohort study

  17483451   Gene-gene interaction associated with neural reward sensitivity

  17585060   Genetic variants in the DRD2 gene moderate the relationship between stressful life events and depressive symptoms in adults: cardiovascular risk in young Finns study.

  17654295   Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation.

  17767146   Meta-analysis of two dopamine D2 receptor gene polymorphisms with tardive dyskinesia in schizophrenia patients.

  17908762   Dopamine receptor D2 gene Taq1A (C32806T) polymorphism modifies the relationship between birth weight and educational attainment in adulthood: 21-year follow-up of the Cardiovascular Risk in Young Finns study.

  17989061   Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review.

  18058343   Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials.

  18063800   Genetically determined differences in learning from errors.

  18077373   Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

  18086475   Gene polymorphism influencing treatment response in psychotic patients in a naturalistic setting.

  18154681   A lesson not learned: allele misassignment.

  18180754   Antipsychotic-induced tardive dyskinesia and polymorphic variations in COMT, DRD2, CYP1A2 and MnSOD genes: a meta-analysis of pharmacogenetic interactions.

  18305461   Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.

  18351593   DRD3, but not COMT or DRD2, genotype affects executive functions in healthy and first-episode psychosis adolescents

  18354387   Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample.

  18366720   Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.

  18563706   The impact of genetic variation in DRD2 and SLC6A3 on smoking cessation in a cohort of participants 1 year after enrollment in a lung cancer screening study.

  18579277   Association between dopamine-related polymorphisms and plasma concentrations of prolactin during risperidone treatment in schizophrenic patients.

  18621654   Comment on "Genetically determined differences in learning from errors".

  18690117   Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers.

  18698520   Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study.

  18715757   Genetic associations with schizophrenia: meta-analyses of 12 candidate genes

  18781856   Genetic underpinnings of tardive dyskinesia: passing the baton to pharmacogenetics.

  18855532   Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia.

  18927395   Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele.

  19065655   Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention Trial.

  19238152   Interaction between dopamine D2 receptor genotype and parental rule-setting in adolescent alcohol use: evidence for a gene-parenting interaction.

  19258022   Now or Later? An fMRI study of the effects of endogenous opioid blockade on a decision-making network.

  19273465   Lack of association of DRD2 rs1800497 (Taq1A) polymorphism with smoking cessation in a nicotine replacement therapy randomized trial.

  19285111   C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo.

  19309284   Haplotype diversity and linkage disequilibrium at DRD2 locus--a study on four population groups of Andhra Pradesh, India.

  19321766   Dopamine DRD2 polymorphism alters reversal learning and associated neural activity.

  19339912   Variants of the dopamine D2 receptor gene and risperidone-induced hyperprolactinemia in children and adolescents.

  19344737   Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents.

  19373123   Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution.

  19393722   Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms.

  19470168   NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.

  19512960   Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.

  19526298   The ANKK1 kinase gene and psychiatric disorders.

  19664686   Potential association of DRD2 and DAT1 genetic variation with heroin dependence.

  19669131   Clinical and pharmacogenetic factors determining withdrawal of non-ergoline dopamine agonists in Parkinson's disease.

  19693267   Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

  19793394   Haplotype frequencies at the DRD2 locus in populations of the East European Plain.

  19796663   Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients.

  19925838   Parental control and the dopamine D2 receptor gene (DRD2) interaction on emotional eating in adolescence.

  20133381   Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans.

  20138949   A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes.

  20146828   Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study.

  20180986   CLOCK is suggested to associate with comorbid alcohol use and depressive disorders.

  20191112   The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.

  20199723   [DRD2/ANKK1 Taq IA polymorphism and early infant temperament].

  20205808   Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients.

  20350135   Prospective association of dopamine-related polymorphisms with smoking cessation in general care.

  20446882   Do candidate genes discriminate patients with an autism spectrum disorder from those with attention deficit/hyperactivity disorder and is there an effect of lifetime substance use disorders?

  20452395   Association of functional variants in the dopamine D2-like receptors with risk for gambling behaviour in healthy Caucasian subjects.

  20482509   Pharmacogenetics of alcohol and alcohol dependence treatment.

  20505554   Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20567893   Association between polymorphisms of the dopamine receptor D2 and catechol-o-methyl transferase genes and cognitive function.

  20714340   Systematic analysis of dopamine receptor genes (DRD1-DRD5) in antipsychotic-induced weight gain.

  20732903   Predicting sensation seeking from dopamine genes. A candidate-system approach.

  20736885   PharmGKB summary: dopamine receptor D2.

  21083670   Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).

  21097659   Interaction effect of functional variants of the BDNF and DRD2/ANKK1 gene is associated with alexithymia in healthy human subjects.

  21150907   Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.

  21162693   Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.

  21168125   TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood

  21172166   Pharmacogenetics of antidepressant response.

  21244440   Risky alcohol use in adolescence: the role of genetics (DRD2, SLC6A4) and coping motives.

  21333900   The role of genetics in IBS

  21456129   Single nucleotide polymorphism genotyping and point mutation detection by ligation on microarrays.

  21499988   Addictive genes and the relationship to obesity and inflammation.

  21502949   Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.

  21519536   No Evidence for an Association between Dopamine D2 Receptor Polymorphisms and Tardive Dyskinesia in Korean Schizophrenia Patients.

  21527290   Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.

  21540761   Association between DRD2/ANKK1 Taq1A genotypes, depression and smoking cessation with nicotine replacement therapy.

  21593733   Multilocus genetic profile for dopamine signaling predicts ventral striatum reactivity.

  21645585   Resting posterior minus frontal EEG slow oscillations is associated with extraversion and DRD2 genotype.

  21663922   Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium.

  21714067   Association between polymorphisms of DRD2 and DRD4 and opioid dependence: evidence from the current studies.

  21728034   Methamphetamine-associated psychosis.

  21749372   Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects.

  21778150   A preliminary analysis of interactions between genotype, retrospective ADHD symptoms, and initial reactions to smoking in a sample of young adults.

  21781348   Genetic polymorphisms involved in dopaminergic neurotransmission and risk of Parkinson's disease in a Japanese population.

  21797889   The relationship between rs3779084 in the dopa decarboxylase (DDC) gene and alcohol consumption is mediated by drinking motives in regular smokers.

  21910549   Genetic predictors of cue- and stress-induced cigarette craving: an exploratory study.

  21948099   Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?