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Normal allele: CC
A variant of a rare protective allele in the norepinephrine transporter gene causes risk of attention deficit hyperactivity disorder.
Polymorphism rs3785143 is related to topics like this:
Dopamine transporter genes The membrane-bound protein called the dopamine transporter (DAT), also known as the... ADHD is it genetic ADHD, a behavioral disorder that usually commences during childhood, is marked by a brief attention...
The membrane-bound protein called the dopamine transporter (DAT), also known as the...
ADHD, a behavioral disorder that usually commences during childhood, is marked by a brief attention...
Research and publications:
17876324 Further evidence of association between two NET single-nucleotide polymorphisms with ADHD.
18821566 SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.
18937296 Replication of a rare protective allele in the noradrenaline transporter gene and ADHD.
18937309 Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.
19698724 Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorder.
20159345 Molecular genetics of attention deficit hyperactivity disorder.
22297068 Differential association between the norepinephrine transporter gene and ADHD: role of sex and subtype.
23185385 Comprehensive phenotype/genotype analyses of the norepinephrine transporter gene (SLC6A2) in ADHD: relation to maternal smoking during pregnancy.
23266789 Adrenergic neurotransmitter system transporter and receptor genes associated with atomoxetine response in attention-deficit hyperactivity disorder children.
24942521 The possible involvement of genetic variants of NET1 in the etiology of attention-deficit/hyperactivity disorder comorbid with oppositional defiant disorder.
27230021 Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traits.
29374517 Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients.
30692908 Differential Genetic Effect of the Norepinephrine Transporter Promoter Polymorphisms on Attention Problems in Clinical and Non-clinical Samples.
31910717 Monoaminergic Genetic Variants, Prefrontal Cortex-Amygdala Circuit, and Emotional Symptoms in Children With ADHD: Exploration Based on the Gene-Brain-Behavior Relationship.
33944622 Role of the norepinephrine transporter polymorphisms in atomoxetine treatment: From response to side effects in children with ADHD.
34797323 Noradrenergic genes polymorphisms and response to methylphenidate in children with ADHD: A systematic review and meta-analysis.
33458869 The influence of dopamine, norepinephrine and serotonin transporters on the pharmacogenetics of atremorine in Parkinson's disease.
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