Normal allele: AA
The striatal polymorphism of the D2 receptor is a novel genetic marker of multiple addiction phenotypes: alcohol, nicotine, heroin and opioid dependence.
Polymorphism rs12364283 is related to topics like this:
Research and publications:
19393722 Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms.
19512960 Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.
21289622 Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy.
21333900 The role of genetics in IBS
21906503 Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.
22579533 Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypes.
22963930 Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.
30093869 Biological Predictors of Clozapine Response: A Systematic Review.
30815277 Unravelling the interaction between the DRD2 and DRD4 genes, personality traits and concussion risk.
31129315 Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain.
35564336 Impact of the DRD2 Polymorphisms on the Effectiveness of the Training Program.