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SNP information rs2242446

RS2242446

Normal allele: TT

Risk of orthostatic intolerance - dizziness or fainting that occurs with prolonged standing or upright posture.

Polymorphism rs2242446 is related to topics like this:

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...


Research and publications:

  17630229   Norepinephrine transporter polymorphisms T-182C and G1287A are not associated with alcohol dependence and its clinical subgroups.

  18081710   Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression.

  18779921   The combined effect of norepinephrine transporter gene and negative life events in major depression of Chinese Han population.

  18821566   SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.

  19693267   Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.

  20863575   Lack of association between response of OROS-methylphenidate and norepinephrine transporter (SLC6A2) polymorphism in Korean ADHD.

  21412203   Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans.

  21687501   Pharmacogenetics of antidepressants.

  23185385   Comprehensive phenotype/genotype analyses of the norepinephrine transporter gene (SLC6A2) in ADHD: relation to maternal smoking during pregnancy.

  23442739   Psychomotor depressive symptoms may differentially respond to venlafaxine.

  23648227   Association between major depressive disorder and the norepinephrine transporter polymorphisms T-182C and G1287A: a meta-analysis.

  24655776   Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder.

  24881125   From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment.

  25912538   Effects of persisting emotional impact from child abuse and norepinephrine transporter genetic variation on antidepressant efficacy in major depression: a pilot study.

  25990886   Impact of monoamine-related gene polymorphisms on hippocampal volume in treatment-resistant depression.

  26508020   Potential involvement of NET polymorphism in serotonin/norepinephrine reuptake inhibitor response in panic disorder.

  26678348   Effects of norepinephrine transporter gene variants on NET binding in ADHD and healthy controls investigated by PET.

  27147943   Neuroendocrinological and Epigenetic Mechanisms Subserving Autonomic Imbalance and HPA Dysfunction in the Metabolic Syndrome.

  27541794   Investigating the genetic basis of attention to facial expressions: the role of the norepinephrine transporter gene.

  28068779   Norepinephrine Transporter Gene Variants and Remission From Depression With Venlafaxine Treatment in Older Adults.

  28454051   No association between SLC6A2, SLC6A3, DRD2 polymorphisms and schizophrenia in the Han Chinese population.

  29198060   No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA.

  29374517   Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients.

  29703117   Association between T-182C, G1287A polymorphism in NET gene and suicidality in major depressive disorder in Chinese patients.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30292339   Meta-analysis on the Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder.

  30692908   Differential Genetic Effect of the Norepinephrine Transporter Promoter Polymorphisms on Attention Problems in Clinical and Non-clinical Samples.

  33290143   The T-182C Polymorphism Enhances Promoter Activity of the Norepinephrine Transporter Gene, but may not be Associated with Antidepressant Response.

  33340618   Association between genetic variants of the norepinephrine transporter gene (SLC6A2) and bipolar I disorder.

  34797323   Noradrenergic genes polymorphisms and response to methylphenidate in children with ADHD: A systematic review and meta-analysis.

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