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SNP information rs5326

RS5326

Normal allele: CC

D1 dopamine receptor gene is associated with the length of the interval between first heroin use and onset of dependence in heroin addicts. Also influences the increased risk of salt-sensitive hypertension.

Polymorphism rs5326 is related to topics like this:

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...

Is drug abuse genetic

There is a significant interest among individuals, particularly those with a familial background of...


Research and publications:

  18821566   SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.

  19500151   Heroin addiction in African Americans: a hypothesis-driven association study.

  20382433   No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia.

  21058046   Genetics of salt-sensitive hypertension.

  21083670   Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).

  21181138   Analysis of genetic variations in the dopamine D1 receptor (DRD1) gene and antipsychotics-induced tardive dyskinesia in schizophrenia.

  21955727   An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.

  22021758   Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort.

  22358648   The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach.

  22963930   Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.

  23133444   Genetic variation in CYP17A1 is associated with arterial stiffness in diabetic subjects.

  23661099   The dopamine receptor D1 gene is associated with the length of interval between first heroin use and onset of dependence in Chinese Han heroin addicts.

  23856854   Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders.

  24790447   Genetic association between the dopamine D1-receptor gene and paranoid schizophrenia in a northern Han Chinese population.

  25179995   Association of dopamine receptor D1 (DRD1) polymorphisms with risperidone treatment response in Chinese schizophrenia patients.

  25233244   Association study of dopamine receptor genes polymorphism with cognitive functions in bipolar I disorder patients.

  25324626   Research in China on the molecular genetics of schizophrenia.

  25875614   Overlapping dopaminergic pathway genetic susceptibility to heroin and cocaine addictions in African Americans.

  29541058   Dopaminergic and opioid pathways associated with impulse control disorders in Parkinson's disease.

  30103286   Association between dopamine receptor gene polymorphisms and effects of risperidone treatment: A systematic review and meta-analysis.

  31192519   Heroin delay discounting and impulsivity: Modulation by DRD1 genetic variation.

  34476566   Methylation quantitative trait locus rs5326 is associated with susceptibility and effective dosage of methadone maintenance treatment for heroin use disorder.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.

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