Normal allele: CC
D1 dopamine receptor gene is associated with the length of the interval between first heroin use and onset of dependence in heroin addicts. Also influences the increased risk of salt-sensitive hypertension.
Polymorphism rs5326 is related to topics like this:
Research and publications:
19500151 Heroin addiction in African Americans: a hypothesis-driven association study.
20382433 No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia.
21058046 Genetics of salt-sensitive hypertension.
21955727 An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.
22963930 Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.
23133444 Genetic variation in CYP17A1 is associated with arterial stiffness in diabetic subjects.
25324626 Research in China on the molecular genetics of schizophrenia.
29541058 Dopaminergic and opioid pathways associated with impulse control disorders in Parkinson's disease.
31192519 Heroin delay discounting and impulsivity: Modulation by DRD1 genetic variation.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.