SNP information rs1611115

Research and publications:

  11170900   A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus.

  14991826   Functional polymorphisms regulating dopamine beta-hydroxylase influence Parkinson's disease.

  15505174   The -1021C->T DBH gene variant is not associated with epilepsy or antiepileptic drug response.

  16616730   A single nucleotide polymorphism at DBH, possibly associated with attention-deficit/hyperactivity disorder, associates with lower plasma dopamine beta-hydroxylase activity and is in linkage disequilibrium with two putative functional single nucl

  17457369   Genotypic and haplotypic associations of the DBH gene with plasma dopamine beta-hydroxylase activity in African Americans.

  17503507   DBH-1021C--u003eT does not affect the risk or age of onset of Parkinson's disease.

  18172755   Correlation of plasma dopamine beta-hydroxylase activity with polymorphisms in DBH gene: a study on Eastern Indian population.

  18180394   Genetic variation within adrenergic pathways determines in vivo effects of presynaptic stimulation in humans

  18330705   Physiogenomic analysis of localized FMRI brain activity in schizophrenia.

  18466599   Linkage studies of catechol-O-methyltransferase (COMT) and dopamine-beta-hydroxylase (DBH) cDNA expression levels

  18722802   Association of dopamine beta-hydroxylase -1021Cu003eT and Parkinson's disease.

  18982239   A functional dopamine-beta-hydroxylase gene promoter polymorphism is associated with impulsive personality styles, but not with affective disorders.

  19540311   Genetics of anxiety and trauma-related disorders.

  19604093   Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients

  19673036   Association of tagging single nucleotide polymorphisms on 8 candidate genes in dopaminergic pathway with schizophrenia in Croatian population.

  19757024   Study on DBH genetic polymorphisms and plasma activity in attention deficit hyperactivity disorder patients from Eastern India.

  19944766   A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia

  20418890   Genome-wide meta-analyses identify multiple loci associated with smoking behavior

  20498626   The role of polymorphisms in dopamine synthesis and metabolism genes and the association of DBH haplotypes with Parkinson's disease among residents of North India.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20621148   Genotype-controlled analysis of serum dopamine β-hydroxylase activity in civilian post-traumatic stress disorder.

  20691427   Genetic associations of brain structural networks in schizophrenia: a preliminary study

  21070631   The dopamine β-hydroxylase -1021C/T polymorphism is associated with risk of Alzheimer's disease in the Epistasis Project.

  21216270   Role of gene-gene/gene-environment interaction in the etiology of eastern Indian ADHD probands.

  21368917   Epistasis between neurochemical gene polymorphisms and risk for ADHD.

  21509519   Linkage analysis of plasma dopamine β-hydroxylase activity in families of patients with schizophrenia.

  21808609   Components of cross-frequency modulation in health and disease.

  22105624   The genetics of attention deficit/hyperactivity disorder in adults, a review.

  22224195   Epigenetics in Developmental Disorder: ADHD and Endophenotypes.

  22640745   The COMT Val158 allele is associated with impaired delayed-match-to-sample performance in ADHD.

  22875483   Identification of a novel ANKK1 and other dopaminergic (DRD2 and DBH) gene variants in migraine susceptibility.

  22906516   Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase.

  23261162   DBH -1021C>T and COMT Val108/158Met genotype are not associated with the P300 ERP in an auditory oddball task.

  23384717   Association between 1603C>T polymorphism of DBH gene and bipolar disorder in a Turkish population.

  23416088   Genotype-independent reduction of plasma dopamine beta-hydroxylase activity in Alzheimer's disease.

  23458673   DBH gene as predictor of response in a cocaine vaccine clinical trial.

  23510745   Positive association between--1021TT genotype of dopamine beta hydroxylase gene and progressive behavior of injection heroin users.

  23692268   Association between dopamine Beta-hydroxylase gene polymorphisms and attention-deficit hyperactivity disorder in korean children.

  23808549   Candidate gene associations with withdrawn behavior.

  23849431   Pharmacogenetic randomized trial for cocaine abuse: disulfiram and α1A-adrenoceptor gene variation.

  23906995   Association of functional DBH genetic variants with alcohol dependence risk and related depression and suicide attempt phenotypes: results from a large multicenter association study.

  24667010   Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome.

  24724887   Pharmacogenetics of naltrexone and disulfiram in alcohol dependent, dually diagnosed veterans.

  24809448   The influence of dopamine β-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence: a preliminary study.

  24892317   Genetic variants associated with addictive behavior in Colombian addicted and non-addicted to heroin or cocaine.

  24986918   The catecholamine biosynthetic enzyme dopamine β-hydroxylase (DBH): first genome-wide search positions trait-determining variants acting additively in the proximal promoter.

  25045619   The Genetics, Neurogenetics and Pharmacogenetics of Addiction.

  25073638   Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis.

  25326128   Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity.

  25658328   Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  26272535   The placebo effect: From concepts to genes.

  26667034   Cannabis and cocaine decrease cognitive impulse control and functional corticostriatal connectivity in drug users with low activity DBH genotypes.

  26868704   Analysis of dopamine beta hydroxylase gene polymorphisms in migraine.

  26959714   Deep sequencing identifies novel regulatory variants in the distal promoter region of the dopamine-β-hydroxylase gene.

  26986136   The Association Between Genetic Variants in the Dopaminergic System and Posttraumatic Stress Disorder: A Meta-Analysis.

  27177268   Association of dopamine beta-hydroxylase (DBH) polymorphisms with susceptibility to Parkinson's disease.

  28139629   [Combination of DAT and DBH gene polymorphisms with a family history of alcohol use disorders increases the risk of withdrawal seizures and delirium tremens during alcohol withdrawal in alcohol-dependent men].

  28647493   Associations between the DBH gene, plasma dopamine β-hydroxylase activity and cognitive measures in Han Chinese patients with schizophrenia.

  29225702   The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus.

  29498170   Pharmacogenetics of Dopamine β-Hydroxylase in cocaine dependence therapy with doxazosin.

  29760667   A DRD2/ANNK1-COMT Interaction, Consisting of Functional Variants, Confers Risk of Post-traumatic Stress Disorder in Traumatized Chinese.

  30187307   Association of the DBH gene rs1611115 polymorphism with Parkinson's disease: a meta-analysis.

  30197492   Testing genetic modifiers of behavior and response to atomoxetine in autism spectrum disorder with ADHD.

  30909233   The Epistasis Project: A multicohort study of the effects of BDNF, DBH, and SORT1 epistasis on Alzheimer's disease risk.

  31082450   Dopamine β-hydroxylase (DBH) is a potential modifier gene associated with Parkinson's disease in East India.

  31183808   The Presynaptic Regulation of Dopamine and Norepinephrine Synthesis Has Dissociable Effects on Different Kinds of Cognitive Conflicts.

  31265749   Dopamine β-hydroxylase (DBH) polymorphism does not influence the clinical course of Wilson's disease in Indian patients.

  31303260   Which Dopamine Polymorphisms Are Functional? Systematic Review and Meta-analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1, and VMAT2.

  31552390   Placebo effects and the molecular biological components involved.

  31771069   Relationship between Alzheimer's disease biomarkers in cerebrospinal fluid and single nucleotide polymorphisms COMT, DBH and MAOB.

  31913053   Association of regulatory variants of dopamine β-hydroxylase with cognition and tardive dyskinesia in schizophrenia subjects.

  33013295   Contribution of five functional gene loci related to dopamine metabolism to Parkinson's disease and multiple system atrophy in a Chinese population.

  33897514   Functional Polymorphisms in Oxytocin and Dopamine Pathway Genes and the Development of Dispositional Compassion Over Time: The Young Finns Study.

  34453125   Molecular genetics of cocaine use disorders in humans.

  34638656   Towards Understanding the Genetic Nature of Vasovagal Syncope.

  34945793   Genetic markers as risk factors for the development of impulsive-compulsive behavior in patients with Parkinson's disease receiving dopaminergic therapy.

  35405990   Associations between Omega-3 Index, Dopaminergic Genetic Variants and Aggressive and Metacognitive Traits: A Study in Adult Male Prisoners.

  35666584   Genetic associations with technical capabilities in English academy football players: a preliminary study.