Normal allele: TT
The dopamine D2 receptor gene is associated with weight gain in schizophrenic patients with long-term treatment with neuroleptics.
Polymorphism rs4436578 is related to topics like this:
Research and publications:
21185230 Antipsychotic drugs and obesity.
24782743 Association of COMT and COMT-DRD2 interaction with creative potential.
24944790 Screening for 392 polymorphisms in 141 pharmacogenes.
27853387 Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics.
27933030 The Association of DRD2 with Insight Problem Solving.
30607769 Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population.
31185074 Genetic Associations with Indoor Tanning Addiction among non-Hispanic White Young Adult Women.
32086104 Association of Genetic Variants of Dopamine and Serotonin In Schizophrenia.