Normal allele: CC
Ankyrin variant 3 (ANK3) is an independent genetic risk factor for bipolar disorder.
Polymorphism rs10994336 is related to topics like this:
Research and publications:
18711365 Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
19088739 Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.
19358880 The genetics of bipolar disorder.
19416921 Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
20185149 Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.
20351715 Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.
20373670 New findings in the genetics of major psychoses.
20940148 The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.
21085053 Database of genetic studies of bipolar disorder.
21304963 The cognitive impact of the ANK3 risk variant for bipolar disorder: initial evidence of selectivity to signal detection during sustained attention.
21353194 Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.
21395576 No association between bipolar disorder risk polymorphisms in ANK3 and CACNA1C and common migraine.
21438140 Association of ANK3 with bipolar disorder confirmed in East Asia.
21438146 Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.
21559500 Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia.
21702894 Is Ankyrin a genetic risk factor for psychiatric phenotypes?
21738484 Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
21767209 ANK3, CACNA1C and ZNF804A gene variants in bipolar disorders and psychosis subphenotype.
21972176 Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples.
22079454 Genome-wide supported risk variant for bipolar disorder alters anatomical connectivity in the human brain.
22105624 The genetics of attention deficit/hyperactivity disorder in adults, a review.
22205951 Genome-wide association study in bipolar patients stratified by co-morbidity.
22498896 Bipolar disorder ANK3 risk variant effect on sustained attention is replicated in a large healthy population.
23025490 Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology.
23070075 Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.
23109352 ANK3 as a risk gene for schizophrenia: new data in Han Chinese and meta analysis.
23507081 Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level.
23796624 The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.
23871474 A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
24016415 Association of a risk allele of ANK3 with cognitive performance and cortical thickness in patients with first-episode psychosis.
24361380 Genetic modulation of working memory deficits by ankyrin 3 gene in schizophrenia.
24655771 Cognitive effects of the ANK3 risk variants in patients with bipolar disorder and healthy individuals.
24914473 Genetic association of LMAN2L gene in schizophrenia and bipolar disorder and its interaction with ANK3 gene polymorphism.
24944871 Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes.
25304227 Analysis of genome-wide significant bipolar disorder genes in borderline personality disorder.
25711502 The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder.
27177275 The ANK3 gene and facial affect processing: An ERP study.
27240527 Effects of ANK3 variation on gray and white matter in bipolar disorder.
28079488 Association analysis of ANK3 variants with bipolar disorder in the Korean population.
28234206 Bipolar disorder risk gene FOXO6 modulates negative symptoms in schizophrenia: a neuroimaging genetics study.
28798405 Progress in genome-wide association studies of schizophrenia in Han Chinese populations.
29684488 Association of CACNA1C with bipolar disorder among the Pakistani population.
31649580 The Association Between Schizophrenia Risk Variants and Creativity in Healthy Han Chinese Subjects.
34421516 ANK3 Gene Polymorphism Rs10994336 Influences Executive Functions by Modulating Methylation in Patients With Bipolar Disorder.