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SNP information rs10994336

RS10994336

Normal allele: CC

Ankyrin variant 3 (ANK3) is an independent genetic risk factor for bipolar disorder.

Polymorphism rs10994336 is related to topics like this:

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...


Research and publications:

  18711365   Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

  19088739   Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.

  19358880   The genetics of bipolar disorder.

  19416921   Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.

  20185149   Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.

  20351715   Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

  20373670   New findings in the genetics of major psychoses.

  20940148   The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.

  21085053   Database of genetic studies of bipolar disorder.

  21304963   The cognitive impact of the ANK3 risk variant for bipolar disorder: initial evidence of selectivity to signal detection during sustained attention.

  21353194   Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.

  21395576   No association between bipolar disorder risk polymorphisms in ANK3 and CACNA1C and common migraine.

  21438140   Association of ANK3 with bipolar disorder confirmed in East Asia.

  21438146   Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.

  21559500   Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia.

  21702894   Is Ankyrin a genetic risk factor for psychiatric phenotypes?

  21738484   Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.

  21767209   ANK3, CACNA1C and ZNF804A gene variants in bipolar disorders and psychosis subphenotype.

  21972176   Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples.

  22005930   Genome-wide study of the association of Alzheimer's disease with psychotic symptoms.

  22079454   Genome-wide supported risk variant for bipolar disorder alters anatomical connectivity in the human brain.

  22105624   The genetics of attention deficit/hyperactivity disorder in adults, a review.

  22205951   Genome-wide association study in bipolar patients stratified by co-morbidity.

  22498896   Bipolar disorder ANK3 risk variant effect on sustained attention is replicated in a large healthy population.

  23025490   Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology.

  23070075   Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.

  23109352   ANK3 as a risk gene for schizophrenia: new data in Han Chinese and meta analysis.

  23507081   Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level.

  23796624   The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.

  23871474   A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.

  24016415   Association of a risk allele of ANK3 with cognitive performance and cortical thickness in patients with first-episode psychosis.

  24361380   Genetic modulation of working memory deficits by ankyrin 3 gene in schizophrenia.

  24655771   Cognitive effects of the ANK3 risk variants in patients with bipolar disorder and healthy individuals.

  24914473   Genetic association of LMAN2L gene in schizophrenia and bipolar disorder and its interaction with ANK3 gene polymorphism.

  24944871   Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes.

  25304227   Analysis of genome-wide significant bipolar disorder genes in borderline personality disorder.

  25711502   The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder.

  27177275   The ANK3 gene and facial affect processing: An ERP study.

  27240527   Effects of ANK3 variation on gray and white matter in bipolar disorder.

  28079488   Association analysis of ANK3 variants with bipolar disorder in the Korean population.

  28234206   Bipolar disorder risk gene FOXO6 modulates negative symptoms in schizophrenia: a neuroimaging genetics study.

  28798405   Progress in genome-wide association studies of schizophrenia in Han Chinese populations.

  29684488   Association of CACNA1C with bipolar disorder among the Pakistani population.

  31649580   The Association Between Schizophrenia Risk Variants and Creativity in Healthy Han Chinese Subjects.

  34421516   ANK3 Gene Polymorphism Rs10994336 Influences Executive Functions by Modulating Methylation in Patients With Bipolar Disorder.

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