Normal allele: TT
The dopamine D2 receptor gene is associated with weight gain in schizophrenic patients with long-term treatment with neuroleptics.
Polymorphism rs1799978 is related to topics like this:
Research and publications:
18305461 Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.
18330705 Physiogenomic analysis of localized FMRI brain activity in schizophrenia.
19156168 Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.
19512960 Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.
20736885 PharmGKB summary: dopamine receptor D2.
21162693 Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction.
21906503 Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters.
22963930 Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.
22992668 Pharmacogenomics knowledge for personalized medicine.
24782743 Association of COMT and COMT-DRD2 interaction with creative potential.
24944790 Screening for 392 polymorphisms in 141 pharmacogenes.
26880915 Pharmacogenetics of Risperidone and Cardiovascular Risk in Children and Adolescents.
27933030 The Association of DRD2 with Insight Problem Solving.
29623639 Pharmacogenetics of Opioid Use Disorder Treatment.
29716536 Dopamine D2 receptor gene polymorphisms and externalizing behaviors in children and adolescents.
30093869 Biological Predictors of Clozapine Response: A Systematic Review.
30607769 Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population.
31129315 Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain.
33519226 Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.
35140610 Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.