Normal allele: TT
Breakage of the dopamine D1 receptor gene increases the risk of paranoid schizophrenia.
Polymorphism rs4867798 is related to topics like this:
Research and publications:
18821566 SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.
20592018 D1 and D2 dopamine receptor-mediated inhibition of activated normal T cell proliferation is lost in jurkat T leukemic cells.
21955727 An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.
23856854 Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders.
24790447 Genetic association between the dopamine D1-receptor gene and paranoid schizophrenia in a northern Han Chinese population.
25179995 Association of dopamine receptor D1 (DRD1) polymorphisms with risperidone treatment response in Chinese schizophrenia patients.
30103286 Association between dopamine receptor gene polymorphisms and effects of risperidone treatment: A systematic review and meta-analysis.
34476566 Methylation quantitative trait locus rs5326 is associated with susceptibility and effective dosage of methadone maintenance treatment for heroin use disorder.