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SNP information rs1076560

RS1076560

Normal allele: CC

A variant of the dopamine D2 receptor gene increases the risk of early Parkinson's disease.

Polymorphism rs1076560 is related to topics like this:

Dopamine transporter genes

The membrane-bound protein called the dopamine transporter (DAT), also known as the...


Research and publications:

  17196743   Association analysis of the dopamine receptor D2 (DRD2) SNP rs1076560 in alcoholic patients.

  18077373   Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory.

  18829695   Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia.

  19176830   Genetically determined interaction between the dopamine transporter and the D2 receptor on prefronto-striatal activity and volume in humans.

  19321766   Dopamine DRD2 polymorphism alters reversal learning and associated neural activity.

  19373123   Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution.

  19393722   Genetic contributions to avoidance-based decisions: striatal D2 receptor polymorphisms.

  19512960   Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.

  19796663   Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients.

  19940176   Functional variation of the dopamine D2 receptor gene is associated with emotional control as well as brain activity and connectivity during emotion processing in humans.

  20146828   Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study.

  20179754   Genetically determined measures of striatal D2 signaling predict prefrontal activity during working memory performance.

  20617039   Alcoholism and alternative splicing of candidate genes.

  20736885   PharmGKB summary: dopamine receptor D2.

  20881944   The roles of dopamine and serotonin in decision making: evidence from pharmacological experiments in humans.

  20934307   The 2nd Schizophrenia International Research Society Conference, 10-14 April 2010, Florence, Italy: summaries of oral sessions.

  21087673   D2 receptor genotype and striatal dopamine signaling predict motor cortical activity and behavior in humans.

  21150907   Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.

  21187413   DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia.

  21289622   Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy.

  21438146   Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.

  21527290   Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood.

  21645585   Resting posterior minus frontal EEG slow oscillations is associated with extraversion and DRD2 genotype.

  21948099   Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?

  21976709   DRD2 genotype-based variation of default mode network activity and of its relationship with striatal DAT binding.

  22102315   Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians.

  22424959   DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience.

  22529823   Connectomic intermediate phenotypes for psychiatric disorders.

  22559203   DRD2 and PPP1R1B (DARPP-32) polymorphisms independently confer increased risk for autism spectrum disorders and additively predict affected status in male-only affected sib-pair families.

  22569179   Rs1076560, a functional variant of the dopamine D2 receptor gene, confers risk of schizophrenia in Han Chinese.

  22745721   Cannabis-dependence risk relates to synergism between neuroticism and proenkephalin SNPs associated with amygdala gene expression: case-control study.

  22829935   Acyl coenzyme A synthetase long-chain 1 (ACSL1) gene polymorphism (rs6552828) and elite endurance athletic status: a replication study.

  22963930   Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  23097719   Current perspectives on the neurobiology of drug addiction: a focus on genetics and factors regulating gene expression.

  23213652   Abstracts of the American College of Neuropsychopharmacology (ACNP) 51st Annual Meeting. December 2-6, 2012. Hollywood, Florida, USA.

  23340505   Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction.

  24322206   Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain.

  24359476   The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction.

  24410775   Moderator effects of working memory on the stability of ADHD symptoms by dopamine receptor gene polymorphisms during development.

  24424781   DRD2 genotype predicts prefrontal activity during working memory after stimulation of D2 receptors with bromocriptine.

  24782743   Association of COMT and COMT-DRD2 interaction with creative potential.

  24819610   DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25563748   Variation in Dopamine D2 and Serotonin 5-HT2A Receptor Genes is Associated with Working Memory Processing and Response to Treatment with Antipsychotics.

  25819021   A review of pharmacogenetic studies of substance-related disorders.

  25829376   Interaction Between Functional Genetic Variation of DRD2 and Cannabis Use on Risk of Psychosis.

  26044620   Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

  26347318   A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples.

  26642826   Network-Dependent Modulation of COMT and DRD2 Polymorphisms in Healthy Young Adults.

  26658939   Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity.

  26926883   Genetic variation and dopamine D2 receptor availability: a systematic review and meta-analysis of human in vivo molecular imaging studies.

  27190009   Dopamine D2 receptor gene variants and response to rasagiline in early Parkinson's disease: a pharmacogenetic study.

  27446594   Genotype frequencies for polymorphisms related to chemotherapy-induced nausea and vomiting in a Japanese population.

  27848079   Cabergoline and prolactinomas: lack of association between DRD2 polymorphisms and response to treatment.

  27867061   Interaction between DRD2 variation and sound environment on mood and emotion-related brain activity.

  27895608   Genetic Consideration of Schizotypal Traits: A Review.

  27933030   The Association of DRD2 with Insight Problem Solving.

  28104410   The DRD2 rs1076560 polymorphism and schizophrenia-related intermediate phenotypes: A systematic review and meta-analysis.

  28692418   Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese.

  28798405   Progress in genome-wide association studies of schizophrenia in Han Chinese populations.

  28822116   Interactions Between Variation in Candidate Genes and Environmental Factors in the Etiology of Schizophrenia and Bipolar Disorder: a Systematic Review.

  29042896   Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population.

  29249680   Dopaminergic polymorphisms associated with drug-induced gait response in Parkinson's disease.

  29653893   Interaction between childhood adversity and functional polymorphisms in the dopamine pathway on first-episode psychosis.

  29881439   The frequency of DRD2 rs1076560 and OPRM1 rs1799971 in substance use disorder patients from the United Arab Emirates.

  30093869   Biological Predictors of Clozapine Response: A Systematic Review.

  30659563   Case-control study analysis of DRD2 gene polymorphisms in drug addicted patients.

  30815277   Unravelling the interaction between the DRD2 and DRD4 genes, personality traits and concussion risk.

  30847741   DRD2 Genotype-Based Variants Modulates D2 Receptor Distribution in Ventral Striatum.

  30967134   A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia.

  31025317   Significant association of DRD2 enhancer variant rs12364283 with heroin addiction in a Pakistani population.

  31129315   Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain.

  31303260   Which Dopamine Polymorphisms Are Functional? Systematic Review and Meta-analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1, and VMAT2.

  31379492   A candidate regulatory variant of the TREM gene cluster increases the risk of Alzheimer's disease by modulating both amyloid-β pathology and neuronal degeneration.

  31555452   BDNF, COMT, and DRD2 polymorphisms and ability to return to work in adult patients with low- and high-grade glioma.

  31744450   Neuropharmacological and Neurogenetic Correlates of Opioid Use Disorder (OUD) As a Function of Ethnicity: Relevance to Precision Addiction Medicine.

  31948125   Personality Traits or Genetic Determinants-Which Strongly Influences E-Cigarette Users?

  32365807   Dopamine Receptor DRD2 Gene rs1076560, Personality Traits and Anxiety in the Polysubstance Use Disorder.

  32588604   Significant association of DRD2 and ANKK1 genes with rural heroin dependence and relapse in men.

  32866209   Detection of epistasis between ACTN3 and SNAP-25 with an insight towards gymnastic aptitude identification.

  32931693   The effect of rs1076560 (DRD2) and rs4680 (COMT) on tardive dyskinesia and cognition in schizophrenia subjects.

  33039854   Contribution of dopamine D2 and D3 receptor functional variants to motor and non-motor symptoms of early-onset Parkinson's disease.

  33529975   Cortical mediation of relationships between dopamine receptor D2 and cognition is absent in youth at risk of bipolar disorder.

  33876249   The Interplay Between Postsynaptic Striatal D2/3 Receptor Availability, Adversity Exposure and Odd Beliefs: A [11C]-Raclopride PET Study.

  34151861   Clinical and genetic analysis of psychosis in Parkinson's disease.

  34440413   Analysis of Selected Variants of DRD2 and ANKK1 Genes in Combat Athletes.

  34485022   Current understanding of the neurobiology of opioid use disorder: An overview.

  34945793   Genetic markers as risk factors for the development of impulsive-compulsive behavior in patients with Parkinson's disease receiving dopaminergic therapy.

  35044623   The role of single nucleotide polymorphisms of monoamine oxidase B, dopamine D2 receptor, and DOPA decarboxylase receptors among patients treated for Parkinson's disease.

  35398727   Correlation between genetic factors and freezing of gait in patients with Parkinson's disease.

  35457347   Influence of COMT (rs4680) and DRD2 (rs1076560, rs1800497) Gene Polymorphisms on Safety and Efficacy of Methylphenidate Treatment in Children with Fetal Alcohol Spectrum Disorders.

  35564336   Impact of the DRD2 Polymorphisms on the Effectiveness of the Training Program.

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