SNP information rs1006737

Research and publications:

  18317468   Whole-genome association study of bipolar disorder.

  18711365   Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

  19358880   The genetics of bipolar disorder.

  19388002   Phenotypic effects of a bipolar liability gene among individuals with major depressive disorder.

  19416921   Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.

  19621016   The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.

  19781653   Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals.

  20098439   CACNA1C (rs1006737) is associated with schizophrenia.

  20226536   Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort.

  20351715   Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

  20373670   New findings in the genetics of major psychoses.

  20638048   Genetic variation in CACNA1C, a gene associated with bipolar disorder, influences brainstem rather than gray matter volume in healthy individuals.

  20679588   Brain function in carriers of a genome-wide supported bipolar disorder variant.

  20723887   Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans.

  20819988   Genetic variation in CACNA1C affects brain circuitries related to mental illness.

  21042317   Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned.

  21078228   Effects of a CACNA1C genotype on attention networks in healthy individuals.

  21085053   Database of genetic studies of bipolar disorder.

  21292451   Initial evidence for the role of CACNA1C on subcortical brain morphology in patients with bipolar disorder.

  21353194   Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.

  21395576   No association between bipolar disorder risk polymorphisms in ANK3 and CACNA1C and common migraine.

  21438146   Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.

  21481336   An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction.

  21559500   Comparative linkage meta-analysis reveals regionally-distinct, disparate genetic architectures: application to bipolar disorder and schizophrenia.

  21654738   Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.

  21767209   ANK3, CACNA1C and ZNF804A gene variants in bipolar disorders and psychosis subphenotype.

  21926972   Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

  22005930   Genome-wide study of the association of Alzheimer's disease with psychotic symptoms.

  22012475   The effects of CACNA1C gene polymorphism on spatial working memory in both healthy controls and patients with schizophrenia or bipolar disorder.

  22105624   The genetics of attention deficit/hyperactivity disorder in adults, a review.

  22212596   Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

  22290120   The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D).

  22365631   Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.

  22373944   Evidence of IQ-modulated association between ZNF804A gene polymorphism and cognitive function in schizophrenia patients.

  22665259   The psychiatric vulnerability gene CACNA1C and its sex-specific relationship with personality traits, resilience factors and depressive symptoms in the general population.

  22914618   Evidence for the impact of the CACNA1C risk allele rs1006737 on 2-year cognitive functioning in bipolar disorder.

  23025490   Ankyrin 3: genetic association with bipolar disorder and relevance to disease pathophysiology.

  23070075   Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.

  23404764   Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity.

  23406546   The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder.

  23437964   Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: a family-based association study.

  23507081   Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level.

  23637625   Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.

  23860750   A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval.

  23871474   A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.

  23880959   CACNA1C genotype explains interindividual differences in amygdala volume among patients with schizophrenia.

  23979604   A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain.

  24269271   The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study.

  24275578   MIR137 gene and target gene CACNA1C of miR-137 contribute to schizophrenia susceptibility in Han Chinese.

  24339136   Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.

  24411473   Hippocampal and frontolimbic function as intermediate phenotype for psychosis: evidence from healthy relatives and a common risk variant in CACNA1C.

  24612926   Genetic variation in CACNA1C affects neural processing in major depression.

  24625753   The impact of MIR137 on dorsolateral prefrontal-hippocampal functional connectivity in healthy subjects.

  24642287   Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects.

  24643163   Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding.

  24944871   Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes.

  25124521   Replication of previous genome-wide association studies of psychiatric diseases in a large schizophrenia case-control sample from Spain.

  25290268   CACNA1C risk variant affects reward responsiveness in healthy individuals.

  25304227   Analysis of genome-wide significant bipolar disorder genes in borderline personality disorder.

  25403839   Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons.

  25588813   Evaluating the association between CACNA1C rs1006737 and schizophrenia risk: A meta-analysis.

  25678966   Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient.

  25843436   CACNA1C SNP rs1006737 associates with bipolar I disorder independent of the Bcl-2 SNP rs956572 variant and its associated effect on intracellular calcium homeostasis.

  25976633   CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity.

  26048451   CACNA1C risk variant is associated with increased amygdala volume.

  26049408   CACNA1C gene and schizophrenia: a case-control and pharmacogenetic study.

  26204268   Schizophrenia Related Variants in CACNA1C also Confer Risk of Autism.

  26210959   Molecular neurobiological clues to the pathogenesis of bipolar disorder.

  26227792   Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population.

  26255836   Evaluation of genetic susceptibility of common variants in CACNA1D with schizophrenia in Han Chinese.

  26401721   Variation in CACNA1C is Associated with Amygdala Structure and Function in Adolescents.

  26475575   A common risk variant in CACNA1C supports a sex-dependent effect on longitudinal functioning and functional recovery from episodes of schizophrenia-spectrum but not bipolar disorder.

  26509803   Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles.

  26541689   CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder.

  26611642   CACNA1C risk variant affects facial emotion recognition in healthy individuals.

  26658939   Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity.

  26756527   The impact of CACNA1C allelic variation on regional gray matter volume in Chinese population.

  27028512   Genetic Evaluation of Schizophrenia Using the Illumina HumanExome Chip.

  27123490   DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient.

  27260792   Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis.

  27271857   CACNA1C hypermethylation is associated with bipolar disorder.

  27276213   Functional Characterization of Schizophrenia-Associated Variation in CACNA1C.

  27482248   Association of CACNA1C Variants with Bipolar Disorder in the Korean Population.

  27601987   Bridging the Gap between Genes and Language Deficits in Schizophrenia: An Oscillopathic Approach.

  27893184   Electrocardiogram Alterations Associated With Psychotropic Drug Use and CACNA1C Gene Variants in Three Independent Samples.

  27895608   Genetic Consideration of Schizotypal Traits: A Review.

  28234206   Bipolar disorder risk gene FOXO6 modulates negative symptoms in schizophrenia: a neuroimaging genetics study.

  28398341   The CACNA1C risk allele rs1006737 is associated with age-related prefrontal cortical thinning in bipolar I disorder.

  28798405   Progress in genome-wide association studies of schizophrenia in Han Chinese populations.

  29042896   Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population.

  29385621   Outgroup emotion processing in the vACC is modulated by childhood trauma and CACNA1C risk variant.

  29541152   Design of FRET Probes for SNP RS1006737, Related to Mood Disorder.

  29684488   Association of CACNA1C with bipolar disorder among the Pakistani population.

  29733866   Interactive effects of early life stress and CACNA1C genotype on cortisol awakening response.

  29942042   A decade in psychiatric GWAS research.

  30079586   The effect of psychosis associated CACNA1C, and its epistasis with ZNF804A, on brain function.

  30216917   Dissecting genetic cross-talk between ADHD and other neurodevelopmental disorders: Evidence from behavioural, pharmacological and brain imaging investigations.

  30607529   Analysis of KCNH2 and CACNA1C schizophrenia risk genes on EEG functional network modulation during an auditory odd-ball task.

  30755265   The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental medicine study.

  30883267   A systematic review of genome-wide association studies of antipsychotic response.