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Systemic lupus erythematosus DNA health report

Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Systemic lupus erythematosus and see a list of existing studies.

SNP polymorphisms related to the topic Systemic lupus erythematosus:

rs1205
rs131654
rs172378
rs241428
rs340630
rs403016
rs419788
rs423490
rs509749
rs548234
rs558702
rs610604
rs633724
rs677066
rs704840TNFSF4 gene polymorphism affects plasma TNFSF4 levels and risk of systemic lupus erythematosus.
rs729302
rs907715Interleukin-21: a novel inflammatory mediator in systemic lupus erythematosus.
rs932859
rs960709
rs979233
rs1128334
rs1143679ITGAM coding variant (rs1143679) influences the risk of kidney disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus.
rs1150754
rs1167796
rs1385374
rs1408077
rs1517352
rs1571344
rs1635852
rs1800629A meta-analysis of 21 studies showed that in European populations, the rs1800629 (A) allele was associated with an increased risk of systemic lupus erythematosus (4-fold higher).
rs1800630
rs1801274
rs1883832The rs1883832 polymorphism of the CD40 gene is associated with serological reactivation of Epstein-Barr virus with conversion to systemic lupus erythematosus in at-risk individuals.
rs1913517
rs1990760Associated with type 1 diabetes mellitus, organ-specific autoimmune diseases including Graves' disease.
rs2004640The IRF5 rs2004640-T allele, a novel genetic factor in systemic lupus erythematosus, is not associated with rheumatoid arthritis.
rs2025935
rs2051549
rs2071278
rs2075799
rs2176082
rs2187668Risk of autoimmune diseases (lupus, gluten disease).
rs2205960Replication of the association of the TNFSF4 promoter region (OX40L) with systemic lupus erythematosus.
rs2230205
rs2230926Multiple polymorphisms in the TNFAIP3 region are independently associated with rheumatoid arthritis and systemic lupus erythematosus.
rs2241524
rs2248932
rs2250656
rs2254546
rs2275247
rs2280381
rs2301271
rs2304256
rs2327832
rs2431099
rs2431697A functional variant of the microRNA-146a promoter modulates its expression and increases the risk of systemic lupus erythematosus.
rs2618476
rs2618479
rs2647012
rs2736340The FAM167A-BLK rs2736340 polymorphism is associated with susceptibility to autoimmune diseases, particularly rheumatoid arthritis and systemic lupus erythematosus.
rs3024505Predisposition variants for ulcerative colitis, Crohn's disease and type 1 diabetes.
rs3024839
rs3024896
rs3093061
rs3129860
rs3130320
rs3131379
rs3733197
rs3734266
rs3738468
rs3745567
rs3748079
rs3818361
rs3821236The STAT4 risk haplotype is associated with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additionally with IRF5 to increase risk.
rs4310446
rs4522865
rs4572884
rs4622329
rs4639966Single nucleotide polymorphism rs4639966 at 11q23.3 is associated with clinical manifestations of systemic lupus erythematosus.
rs4684256
rs4728142Validation of IRF5 as a multiple sclerosis risk gene: putative role in human herpes virus-6 infection.
rs4794067
rs4807895
rs4852324
rs4917014
rs4948496
rs4963128
rs5029939Association of TNFAIP3 gene polymorphism ( rs5029939 ) with susceptibility and clinical phenotype of systemic lupus erythematosus.
rs5744168
rs5754217
rs6049839
rs6445975
rs6590330
rs6656401An updated analysis of 85,939 samples confirms an association between the CR1 rs6656401 polymorphism and Alzheimer's disease.
rs6695567
rs6705628
rs6804441
rs6835457
rs7097397
rs7172677
rs7186852
rs7197475
rs7329174
rs75748651.3-fold risk of rheumatoid arthritis
rs7582694
rs7812879
rs8023715
rs9270984
rs9271100
rs9275572
rs9275596
rs9276606
rs9303277
rs9888739
rs9937837
rs10036748
rs10168266
rs10181656
rs10276619
rs10488631The interferon regulatory factor 5 (IRF5) gene variant causes a 2-fold increased risk of systemic lupus erythematosus
rs10498070
rs10499197Risk haplotype encompassing TNFAIP3 associated with lupus nephritis and haematological manifestations.
rs10516487Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
rs10779339
rs10845606
rs10857712
rs10911390
rs10911628
rs10954213
rs11073328
rs11101442
rs11117956
rs11118131
rs11150610
rs11569523
rs11574637
rs11717455
rs11860650ITGAM gene polymorphisms confer a higher risk of discoid cutaneous lupus erythematosus than systemic lupus erythematosus.
rs11889341
rs12034383
rs12141391
rs12537284
rs12599402
rs12629106
rs12711490
rs12822507
rs12949531
rs13239597
rs13277113The rs13277113 genotype associated with the BLK pathway is more common in patients with systemic lupus erythematosus and is associated with low gene expression and increased frequency of exacerbations.
rs13306575
rs13385731RasGRP3 gene variation is associated with clinical features of systemic lupus erythematosus.
rs17039212
rs17047631
rs17250932
rs17266594
rs34015031
rs35131781
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