Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Systemic lupus erythematosus and see a list of existing studies.
SNP polymorphisms related to the topic Systemic lupus erythematosus:
|TNFSF4 gene polymorphism affects plasma TNFSF4 levels and risk of systemic lupus erythematosus.
|Interleukin-21: a novel inflammatory mediator in systemic lupus erythematosus.
|ITGAM coding variant (rs1143679) influences the risk of kidney disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus.
|A meta-analysis of 21 studies showed that in European populations, the rs1800629 (A) allele was associated with an increased risk of systemic lupus erythematosus (4-fold higher).
|The rs1883832 polymorphism of the CD40 gene is associated with serological reactivation of Epstein-Barr virus with conversion to systemic lupus erythematosus in at-risk individuals.
|Associated with type 1 diabetes mellitus, organ-specific autoimmune diseases including Graves' disease.
|The IRF5 rs2004640-T allele, a novel genetic factor in systemic lupus erythematosus, is not associated with rheumatoid arthritis.
|Risk of autoimmune diseases (lupus, gluten disease).
|Replication of the association of the TNFSF4 promoter region (OX40L) with systemic lupus erythematosus.
|Multiple polymorphisms in the TNFAIP3 region are independently associated with rheumatoid arthritis and systemic lupus erythematosus.
|A functional variant of the microRNA-146a promoter modulates its expression and increases the risk of systemic lupus erythematosus.
|The FAM167A-BLK rs2736340 polymorphism is associated with susceptibility to autoimmune diseases, particularly rheumatoid arthritis and systemic lupus erythematosus.
|Predisposition variants for ulcerative colitis, Crohn's disease and type 1 diabetes.
|The STAT4 risk haplotype is associated with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additionally with IRF5 to increase risk.
|Single nucleotide polymorphism rs4639966 at 11q23.3 is associated with clinical manifestations of systemic lupus erythematosus.
|Validation of IRF5 as a multiple sclerosis risk gene: putative role in human herpes virus-6 infection.
|Association of TNFAIP3 gene polymorphism ( rs5029939 ) with susceptibility and clinical phenotype of systemic lupus erythematosus.
|An updated analysis of 85,939 samples confirms an association between the CR1 rs6656401 polymorphism and Alzheimer's disease.
|1.3-fold risk of rheumatoid arthritis
|The interferon regulatory factor 5 (IRF5) gene variant causes a 2-fold increased risk of systemic lupus erythematosus
|Risk haplotype encompassing TNFAIP3 associated with lupus nephritis and haematological manifestations.
|Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
|ITGAM gene polymorphisms confer a higher risk of discoid cutaneous lupus erythematosus than systemic lupus erythematosus.
|The rs13277113 genotype associated with the BLK pathway is more common in patients with systemic lupus erythematosus and is associated with low gene expression and increased frequency of exacerbations.
|RasGRP3 gene variation is associated with clinical features of systemic lupus erythematosus.