SNP information rs6656401

Research and publications:

  19734903   Genome-wide association study identifies CLU and CR1 variants associated with Alzheimer's disease.

  20236449   Genetics of Alzheimer disease in the pre- and post-GWAS era.

  20534741   Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

  20558149   Complement receptor 1 polymorphism and risk of late-onset Alzheimer's disease.

  20570404   Association of CLU and PICALM variants with Alzheimer's disease.

  20594621   Genetic architecture of Alzheimer's disease: beyond APP, PSEN and APOE.

  20739100   Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.

  21124753   Alzheimer's disease: diagnosis, prognosis and path to prevention.

  21152065   A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis.

  21347408   Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers of Alzheimer's disease.

  21358043   PICALM and CR1 variants are not associated with sporadic Alzheimer's disease in Chinese patients.

  21391232   CR1 is associated with amyloid plaque burden and age-related cognitive decline.

  21403675   Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites.

  21547229   Neuroimaging indicators as endophenotypes in Alzheimer's disease.

  21700265   Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate.

  21726919   CR1 genotype is associated with entorhinal cortex volume in young healthy adults.

  21766012   Alzheimer's disease genes are associated with rates of cognitive aging in the Lothian cohorts born in 1921 and 1936.

  21912625   An exploratory study on CLU, CR1 and PICALM and Parkinson disease.

  22015308   Polymorphisms of CR1, CLU and PICALM determine susceptibility to Alzheimer's disease in a population of southern China.

  22054870   A genome-wide scan for common variants affecting the rate of age-related cognitive decline.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22216291   Association between IgM anti-herpes simplex virus and plasma amyloid-beta levels.

  22244847   Alzheimer's disease risk factor receptor 1 is associated with depression.

  22262751   Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.

  22343410   A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline.

  22482072   Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.

  22960360   Association of CR1 polymorphism with late-onset Alzheimer's disease in a Chinese Han population: a meta-analysis.

  23573206   Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

  23582656   The p.Ser1610Thr variant encoding complement receptor 1 in Alzheimer's disease and related endophenotypes.

  24176626   Evaluation of late-onset Alzheimer disease genetic susceptibility risks in a Canadian population.

  24443964   Review: Genetics of Alzheimer's disease;

  24621201   Tag SNPs in complement receptor-1 contribute to the susceptibility to non-small cell lung cancer.

  24878768   Updated analysis of 85,939 samples confirms association between CR1 rs6656401 polymorphism and Alzheimer's disease.

  24996192   Meta-analysis of the association between CR1 polymorphisms and risk of late-onset Alzheimer's disease.

  25108264   Genomics in neurological disorders.

  25188341   Genome-wide association meta-analysis of the neuropathological features of Alzheimer's disease and related dementias.

  25426068   Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.

  25649863   Identifying genetic interactions associated with late-onset Alzheimer's disease.

  25666996   Alzheimer's disease is associated with low density of the long CR1 isoform.

  25668194   Examination of candidate exonic variants for association to Alzheimer disease in the Amish.

  26000043   Complement receptor 1 genetic variants contribute to the susceptibility to gastric cancer in chinese population.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26732597   GWAS-associated loci and neuroimaging techniques in Alzheimer's disease.

  26914463   Analysis of the putative role of CR1 in Alzheimer's disease: genetic association, expression and function.

  26919393   Alzheimer's disease risk polymorphisms regulate gene expression at the ZCWPW1 and CELF1 loci.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27313629   Modeling Alzheimer's disease using induced pluripotent stem cells: current issues and future challenges.

  27340842   Evaluating a genetic risk score to improve Alzheimer's disease risk prediction.

  27371493   Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.

  27453991   A new approach to multi-SNP GWAS and its application in Alzheimer's disease.

  27662287   Pathway-specific polygenic risk scores as predictors of β-amyloid deposition and cognitive function in a sample at increased risk of Alzheimer's disease.

  27799753   Mutations associated with early onset Alzheimer's disease have been found in Asian countries.

  28477215   Validation of GWAS variants from microglial genes involved in Alzheimer's disease.

  28549481   The genetics of late-onset Alzheimer's disease implicates microglial pathways in disease risk.

  29504051   Updated meta-analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 variants in Alzheimer's disease.

  29686679   Sparking Fire Under the Skin? Answers From the Association of Complement Genes With Pemphigus Foliaceus.

  30128317   Genetic risk of Alzheimer's disease is reduced in primary age-related tauopathy: a potential model of resistance?

  30503753   Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.

  32388800   First report of CR1 polymorphisms and soluble CR1 levels associated with late-onset Alzheimer's disease (LOAD) in Latin America.

  32432316   Complement receptor 1 genetic polymorphisms contribute to sporadic susceptibility to Alzheimer's disease in Caucasians: a meta-analysis.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  34347684   Explore the role of CR1 genetic variants in susceptibility to late-onset Alzheimer's disease.

  34603005   A Multimodal Risk Network Predicts Executive Function Trajectories in Non-demented Aging.

  34752346   Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.

  34975449   Structural covariance network as an endophenotype in Alzheimer's disease susceptibility single nucleotide polymorphisms and correlations with cognitive outcomes.