SNP information rs11889341

Research and publications:

  17932559   Association of STAT4 with rheumatoid arthritis in the Korean population.

  18434327   Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

  18516230   Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

  18579578   A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

  18803832   Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.

  19674979   Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

  19737838   A haplotype in STAT4 gene associated with rheumatoid arthritis in Caucasians is not associated in the Han Chinese population, but with the presence of rheumatoid factor.

  19950257   Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines.

  20176035   Association of signal transducer and activator of transcription 4 genetic variants with extra-intestinal manifestations in inflammatory bowel disease.

  20233754   Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.

  20237121   Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans.

  20309874   Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.

  20454450   Evidence that STAT4 is a common autoimmune gene: rs7574865 is associated with Crohn's disease of the colon and early onset of the disease.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21120996   Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans.

  21683716   Signal transducer and activator of transcription 4 gene polymorphisms associated with rheumatoid arthritis in Northwestern Chinese Han population.

  22479607   Analysis of IL12B gene variants in inflammatory bowel disease.

  22483685   Interaction between IL17A, IL23R and STAT4 polymorphisms confers susceptibility to intestinal Behçet's disease in the Korean population.

  22569826   Abnormal genetic and epigenetic changes in signal transducer and activator of transcription 4 in the pathogenesis of inflammatory bowel diseases.

  23226040   Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies.

  23251581   Meta-analysis of 125 rheumatoid arthritis-related single nucleotide polymorphisms studied in the past two decades.

  24386384   Association of STAT4 polymorphism with severe renal insufficiency in lupus nephritis.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25328554   Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes.

  25829184   STAT4 genetic polymorphisms association with spontaneous clearance of hepatitis B virus infection.

  25979711   Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?

  26106387   Pathogenesis of Systemic Sclerosis.

  26606652   Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.

  26663301   Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

  26798662   Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype.

  26880555   Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.

  27235632   STAT4 single nucleotide gene polymorphisms and susceptibility to endometriosis-related infertility.

  27444301   Association of STAT4 polymorphisms with hepatitis B virus infection and clearance in Chinese Han population.

  27693588   Genetics of human lupus nephritis.

  27906046   Chromatin landscapes and genetic risk in systemic lupus.

  27957241   Recent advances in the diagnosis and treatment of primary biliary cholangitis.

  29912393   A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

  30770922   Genetics and epigenetics of primary Sjögren's syndrome.

  30887509   Influence of STAT4 gene polymorphisms in the pathogenesis of endometriosis.

  31475028   Host Genetic Determinants of Hepatitis B Virus Infection.

  33766895   Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus.

  34100914   A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case-control study.

  34176465   Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population.

  35184318   Genome-wide meta-analysis identifies susceptibility loci for autoimmune hepatitis type 1.