SNP information rs2736340

Research and publications:

  19503088   REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

  19644876   Association of STAT4 and BLK, but not BANK1 or IRF5, with primary antiphospholipid syndrome.

  19740902   Replication of association between FAM167A(C8orf13)-BLK region and rheumatoid arthritis in a Japanese population.

  19796918   Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations.

  19838195   A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

  20018022   Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.

  20075733   Recent advances in the genetics of rheumatoid arthritis.

  20156505   Role of the C8orf13-BLK region in biopsy-proven giant cell arteritis.

  20169177   Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

  20392289   Genetic associations in type I interferon related pathways with autoimmunity.

  20441431   Recent advances in the genetics of systemic lupus erythematosus.

  20453842   Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

  20510233   Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20807474   The genetics of systemic sclerosis.

  20833654   Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21068098   Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

  21211616   Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

  21408207   Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

  21595938   Polymorphisms associated with rheumatoid arthritis do not protect against Alzheimer's disease.

  21765104   Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.

  21826374   Selective IgA deficiency in autoimmune diseases.

  21905002   Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus.

  21978998   Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.

  21980439   A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

  22102179   Genetics of systemic sclerosis: an update.

  22294642   Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.

  22328738   Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.

  22536486   Lupus nephritis: an overview of recent findings.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  22696686   Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein.

  23023776   European genetic ancestry is associated with a decreased risk of lupus nephritis.

  23121884   Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.

  23124848   Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.

  23678157   Integrative analyses for functional mechanisms underlying associations for rheumatoid arthritis.

  23840476   Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.

  23899688   Polymorphisms in FAM167A-BLK, but not in BANK1, are associated with primary Sjögren's syndrome in a Chinese Han population.

  23983088   Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders.

  24068971   Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

  24449572   Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

  24577620   8p22-23-rs2254546 as a susceptibility locus for Kawasaki disease: a case-control study and a meta-analysis.

  24632671   Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility.

  24702955   Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.

  25328554   Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes.

  25470816   Possible single-nucleotide polymorphism loci associated with systemic sclerosis susceptibility: a genetic association study in a Chinese Han population.

  25545785   The effect of inversion at 8p23 on BLK association with lupus in Caucasian population.

  25645453   Systematic confirmation study of GWAS-identified genetic variants for Kawasaki disease in a Chinese population.

  25846585   Single nucleotide polymorphisms in the FAM167A-BLK gene are associated with polymyositis/dermatomyositis in the Han Chinese population.

  25861330   Update of genetic susceptibility in patients with Kawasaki disease.

  26092158   IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups.

  26106387   Pathogenesis of Systemic Sclerosis.

  26182267   [Genetic susceptibility in children with incomplete Kawasaki disease].

  26420661   Gene-gene interaction of ATG5, ATG7, BLK and BANK1 in systemic lupus erythematosus.

  26632378   Recent Advances in Kawasaki Disease.

  26843965   Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis.

  27067206   Association between BLK polymorphisms and susceptibility to SLE : A meta-analysis.

  27105348   Association of FAM167A-BLK rs2736340 Polymorphism with Susceptibility to Autoimmune Diseases: A Meta-Analysis.

  27171184   Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.

  27313329   Genetic risk factors for sclerotic graft-versus-host disease.

  27630202   Establishment of Kawasaki disease database based on metadata standard.

  27864698   BLK pathway-associated rs13277113 GA genotype is more frequent in SLE patients and associated with low gene expression and increased flares.

  27906046   Chromatin landscapes and genetic risk in systemic lupus.

  28885337   B-cell lymphocyte kinase polymorphisms rs13277113, rs2736340, and rs4840568 and risk of autoimmune diseases: A meta-analysis.

  30351170   Polymorphisms of FAM167A-BLK Region Confer Risk of Autoimmune Thyroid Disease.

  30589937   Associations of secreted phosphoprotein 1 and B lymphocyte kinase gene polymorphisms with autoimmune thyroid disease.

  31134304   BLK and BANK1 polymorphisms and interactions are associated in Mexican patients with systemic lupus erythematosus.

  31872004   Data on a genome-wide association study of type 2 diabetes in a Maya population.

  32153635   Association of BLK and BANK1 Polymorphisms and Interactions With Rheumatoid Arthritis in a Latin-American Population.

  33147747   Pathogenic Single Nucleotide Polymorphisms on Autophagy-Related Genes.

  33975174   Polymorphisms in TNFAIP3, but not in STAT4, BANK1, BLK, and TNFSF4, are associated with susceptibility to Takayasu arteritis.

  35088123   Genetics of rheumatoid arthritis.