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SNP information rs2205960

RS2205960

Normal allele: GG

Replication of the association of the TNFSF4 promoter region (OX40L) with systemic lupus erythematosus.

Polymorphism rs2205960 is related to topics like this:

Lupus is it genetic

It is now well understood that lupus is caused by both environmental and genetic factors. At...


Research and publications:

  19092840   Replication of the TNFSF4 (OX40L) promoter region association with systemic lupus erythematosus.

  19357697   Association of BANK1 and TNFSF4 with systemic lupus erythematosus in Hong Kong Chinese.

  19778912   Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis.

  19838195   A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

  20441431   Recent advances in the genetics of systemic lupus erythematosus.

  20848568   Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.

  20881011   Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21068098   Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

  21379322   Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

  21408207   Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

  21719445   Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.

  21792837   Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.

  21801342   Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits.

  21905002   Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus.

  22102179   Genetics of systemic sclerosis: an update.

  22110124   Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.

  22291604   A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.

  22422496   Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis.

  22541939   Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study.

  22640752   The genetics of lupus: a functional perspective.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  22820624   Associations between TNFSF4 and TRAF1-C5 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.

  22850862   Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis.

  22972380   Investigation of genetic risk factors for chronic adult diseases for association with preterm birth

  23049788   Further evidence of subphenotype association with systemic lupus erythematosus susceptibility loci: a European cases only study.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  23874208   Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

  24653663   Systemic Lupus Erythematosus: Old and New Susceptibility Genes versus Clinical Manifestations.

  24946689   Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25328554   Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes.

  25777745   Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance.

  26106387   Pathogenesis of Systemic Sclerosis.

  26663301   Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

  26798662   Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype.

  26880555   Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.

  27313329   Genetic risk factors for sclerotic graft-versus-host disease.

  27519474   TNFSF4 polymorphisms are associated with systemic lupus erythematosus in the Malaysian population.

  27536670   Lupus Nephritis in Asia: Clinical Features and Management.

  27693588   Genetics of human lupus nephritis.

  27872495   Association of TNFSF4 polymorphisms with Vogt-Koyanagi-Harada and Behçet disease in Han Chinese.

  28470010   Positive Association between ANKRD55 Polymorphism 7731626 and Dermatomyositis/Polymyositis with Interstitial Lung Disease in Chinese Han Population.

  29032462   Association of TNFSF4 Polymorphisms with Neuromyelitis Optica Spectrum Disorders in a Chinese Population.

  29214033   Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.

  30041578   Association of ITGAM, TNFSF4, TNFAIP3 and STAT4 gene polymorphisms with risk of systemic lupus erythematosus in a North Indian population.

  30179587   Precision medicine in lupus nephritis: can biomarkers get us there?

  31299880   Association of TNFSF4 rs1234315, rs2205960 polymorphisms and systemic lupus erythematosus susceptibility: a meta-analysis.

  32208776   Associations between TNFSF4 gene polymorphisms (rs2205960 G > A, rs704840 T > G and rs844648 G > A) and susceptibility to autoimmune diseases in Asians: a meta-analysis.

  32809147   TNFSF4 is a risk factor to systemic lupus erythematosus in a Latin American population.

  33161796   Association of TNFSF4 Gene Polymorphisms and Plasma TNFSF4 Level with Risk of Systemic Lupus Erythematosus in a Chinese Population.

  33894768   Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes.

  33975174   Polymorphisms in TNFAIP3, but not in STAT4, BANK1, BLK, and TNFSF4, are associated with susceptibility to Takayasu arteritis.

  34464884   Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction.

  34538280   Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis.

  35743441   The Impacts of the Clinical and Genetic Factors on Chronic Damage in Caucasian Systemic Lupus Erythematosus Patients.

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