SNP information rs907715

Research and publications:

  17720724   Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.

  19644854   A polymorphism within IL21R confers risk for systemic lupus erythematosus.

  20553587   Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

  20652041   Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus.

  20848568   Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.

  20881011   Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.

  21425124   Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.

  21719445   Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.

  22110124   Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.

  22752563   A single nucleotide polymorphism of IL-21 gene is associated with systemic lupus erythematosus in a Chinese population.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  23172754   Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.

  23236436   Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus.

  23288348   IL-21 gene polymorphism is associated with the prognosis of breast cancer in Chinese populations.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  24389496   Interleukin (IL)-21 promoter polymorphism increases the risk of thyroid cancer in Chinese population.

  24434811   The association of interleukin-21 polymorphisms with interleukin-21 serum levels and risk of systemic lupus erythematosus.

  24879484   Interleukin-21 polymorphism affects gene expression and is associated with risk of ischemic stroke.

  24944624   Association between the rs907715 polymorphism of the IL-21 gene and Graves' disease in a southern Chinese population.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25074442   Association of IL-21 polymorphisms (rs907715, rs2221903) with susceptibility to multiple autoimmune diseases: a meta-analysis.

  25126827   Functional interleukin-21 polymorphism is a protective factor of diffuse large B-cell lymphoma.

  26106387   Pathogenesis of Systemic Sclerosis.

  26345892   Association between IL-21 polymorphism and systemic lupus erythematosus: a meta-analysis.

  26798662   Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype.

  26990619   Genetic Association Between IL-21 Polymorphisms and Cryptorchidism in a Chinese Han Population.

  27122304   Association between interleukin-21 gene polymorphisms (rs12508721) and HBV-related hepatocellular carcinoma.

  27295539   Association between polymorphisms in IL21 gene and risk for sepsis.

  27570418   Hepatitis-related hepatocellular carcinoma: Insights into cytokine gene polymorphisms.

  27635407   Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?

  29879024   Role of interleukin-21 and interleukin-21 receptor polymorphisms in the treatment of HBeAg-positive chronic hepatitis B patients with peginterferon.

  30474404   Polymorphisms in Th17-related genes and the pathogenesis of autoimmune thyroid disease.

  31282133   Correlation between rs907715, rs2221903 and rs12508721 polymorphisms in IL-21 and susceptibility to hepatitis B.

  32206179   Association between interleukin-21 gene rs907715 polymorphism and gastric precancerous lesions in a Chinese population.

  32206489   Genes and novel sRNAs involved in PAHs degradation in marine bacteria Rhodococcus sp. P14 revealed by the genome and transcriptome analysis.

  33673829   Plasma interleukin-21 levels and genetic variants are associated with susceptibility to rheumatoid arthritis.