SNP information rs2230926

Research and publications:

  19165918   Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

  19165919   Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus.

  19169254   Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

  19387456   Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.

  19417005   Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

  19439038   Complex genetic association of 6q23 with autoimmune rheumatic conditions.

  19774492   A single-nucleotide polymorphism of the TNFAIP3 gene is associated with systemic lupus erythematosus in Chinese Han population.

  20112363   The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.

  20169177   Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

  20483768   African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity.

  20617138   Association of TNFAIP3 polymorphism with susceptibility to systemic lupus erythematosus in a Japanese population.

  20822710   Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis.

  20849588   Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study.

  20876667   Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21060334   Genetic susceptibility to systemic lupus erythematosus in the genomic era.

  21208380   The association between BANK1 and TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.

  21326317   Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.

  21336280   Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.

  21622953   ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework.

  21905002   Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus.

  21917936   Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.

  21980439   A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

  22087647   Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population.

  22113471   TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis.

  22291604   A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.

  22402800   Associations between TNFAIP3 gene polymorphisms and rheumatoid arthritis: a meta-analysis.

  22407130   Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up.

  22488580   Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity.

  22541939   Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study.

  22640752   The genetics of lupus: a functional perspective.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  22924496   Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.

  23049601   Genetics of myasthenia gravis: a case-control association study in the Hellenic population.

  23049788   Further evidence of subphenotype association with systemic lupus erythematosus susceptibility loci: a European cases only study.

  23227085   Genetics of SLE: functional relevance for monocytes/macrophages in disease.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  23393188   Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.

  23911423   Genetic interaction between genes involved in NF-κB signaling pathway in systemic lupus erythematosus.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24489017   TNFAIP3 gene polymorphisms associated with differential susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Korean population.

  24728327   Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

  24884566   Single nucleotide polymorphisms in TNFAIP3 were associated with the risks of rheumatoid arthritis in northern Chinese Han population.

  24946689   Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus.

  24971370   Alternative expression pattern of MALT1-A20-NF-κB in patients with rheumatoid arthritis.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25050625   Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese population.

  25337792   Genetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population.

  25473424   Enhancer variants: evaluating functions in common disease.

  25674272   TNFAIP3 rs2230926 polymorphisms in rheumatoid arthritis of southern Chinese Han population: a case-control study.

  25806576   The polymorphisms of tumor necrosis factor-induced protein 3 gene may contribute to the susceptibility of chronic primary immune thrombocytopenia in Chinese population.

  25980667   Pharmacogenetics of treatment response in psoriatic arthritis.

  26143186   Characteristics of A20 gene polymorphisms and clinical significance in patients with rheumatoid arthritis.

  26324017   Immunogenetics of systemic lupus erythematosus: A comprehensive review.

  26338037   Germline variation of TNFAIP3 in primary lymphoma associated with Sjögren's syndrome.

  26663301   Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

  26846592   Single nucleotide polymorphisms of TNFAIP3 are associated with systemic lupus erythematosus in Han Chinese population.

  26986245   Development of a high-resolution melting method for the screening of TNFAIP3 gene mutations.

  27057306   Host nucleotide polymorphism in hepatitis B virus-associated hepatocellular carcinoma.

  27338350   Rheumatoid Arthritis: The Stride from Research to Clinical Practice.

  27536202   Association of the polymorphisms of TRAF1 (rs10818488) and TNFAIP3 (rs2230926) with rheumatoid arthritis and systemic lupus erythematosus and their relationship to disease activity among Egyptian patients.

  27726311   Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus risk: an updated meta-analysis.

  28199970   Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis.

  28296250   Different genetic alteration of A20 in a Sézary syndrome case with Vα2-Jα22 T cell clone.

  28448618   rs10499194 polymorphism in the tumor necrosis factor-α inducible protein 3 (TNFAIP3) gene is associated with type-1 autoimmune hepatitis risk in Chinese Han population.

  28639493   Pathway analysis to identify genetic variants associated with efficacy of adalimumab in rheumatoid arthritis.

  28888761   Associations Between TNFAIP3 Gene Polymorphisms and Rheumatoid Arthritis Risk: A Meta-analysis.

  29783072   Association of TNFAIP3 and TNIP1 polymorphisms with systemic lupus erythematosus risk: A meta-analysis.

  30206443   Genetic polymorphism in psoriasis and its meaning for the treatment efficacy in the future.

  30529365   Functional variants of TNFAIP3 are associated with systemic lupus erythematosus in a cohort of Chinese Han population.

  30662920   TNFAIP3 F127C coding alteration in patients with Greek primary Sjögren's syndrome.

  30770922   Genetics and epigenetics of primary Sjögren's syndrome.

  30923465   SNP variations in the IL10, TNFα and TNFAIP3 genes in patients with dry eye syndrome and Sjögren's syndrome.

  31131138   Identification of functional missense single-nucleotide polymorphisms in TNFAIP3 in a predominantly Hispanic population.

  31217170   Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.

  31300459   Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus.

  31530986   Associations of TRAF1/C5 rs10818488 and rs3761847 polymorphisms with genetic susceptibility to rheumatoid arthritis: a case-control study and updated meta-analysis.

  31534975   TNFAIP3 Gene Polymorphisms in Three Common Autoimmune Diseases: Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Primary Sjogren Syndrome-Association with Disease Susceptibility and Clinical Phenotypes in Italian Patients.

  32334614   Synergistic activation of NF-κB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk.

  32406335   Lack of association between a disease-susceptible single-nucleotide polymorphism, rs2230926 of TNFAIP3, and tumour necrosis factor inhibitor therapeutic failure in Japanese patients with rheumatoid arthritis.

  33287909   The haplotypes of various TNF related genes associated with scleritis in Chinese Han.

  33975174   Polymorphisms in TNFAIP3, but not in STAT4, BANK1, BLK, and TNFSF4, are associated with susceptibility to Takayasu arteritis.

  34199962   Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach.

  34306371   Bioinformatics analysis of epigenetic and SNP-related molecular markers in systemic lupus erythematosus.

  34464884   Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction.

  34840214   Clinicopathologic Characteristics and A20 Mutation in Primary Thyroid Lymphoma.

  34847931   Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes.

  35107652   A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.

  35382527   Genetics of systemic sclerosis.

  35490943   Lack of association between the TNFAIP3 rs2230926 variant and rheumatoid arthritis-associated lymphoma.

  36096187   HFE hemochromatosis in African Americans: Prevalence estimates of iron overload and iron overload-related disease.