SNP information rs3821236

Research and publications:

  18516230   Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

  18579578   A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

  19019891   STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.

  19165918   Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

  19287509   Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis.

  19333953   High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.

  19440199   Recent insights into the genetic basis of systemic lupus erythematosus.

  19644876   Association of STAT4 and BLK, but not BANK1 or IRF5, with primary antiphospholipid syndrome.

  20383147   Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus.

  20392289   Genetic associations in type I interferon related pathways with autoimmunity.

  20652065   Interferon alpha in systemic lupus erythematosus.

  20722033   The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21750679   Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.

  21852963   Pervasive sharing of genetic effects in autoimmune disease.

  22440820   IRF5 polymorphism predicts prognosis in patients with systemic sclerosis.

  22536486   Lupus nephritis: an overview of recent findings.

  24926413   Design and implementation of a randomized controlled trial of genomic counseling for patients with chronic disease.

  25332064   An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3.

  25777745   Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance.

  26689915   Application of Various Statistical Models to Explore Gene-Gene Interactions in Folate, Xenobiotic, Toll-Like Receptor and STAT4 Pathways that Modulate Susceptibility to Systemic Lupus Erythematosus.

  27134258   Analysis of Systemic Sclerosis-associated Genes in a Turkish Population.

  29476163   Genetic predictors of systemic sclerosis-associated interstitial lung disease: a review of recent literature.

  30770922   Genetics and epigenetics of primary Sjögren's syndrome.

  31872004   Data on a genome-wide association study of type 2 diabetes in a Maya population.

  32973967   SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women.

  33894768   Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes.

  34176465   Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population.

  35382527   Genetics of systemic sclerosis.