SNP information rs5029939

Research and publications:

  19165918   Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

  19169254   Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

  19387456   Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.

  19474294   Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

  19849816   Genetics of rheumatic disease.

  20483768   African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity.

  20511617   Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population.

  20617138   Association of TNFAIP3 polymorphism with susceptibility to systemic lupus erythematosus in a Japanese population.

  20852893   Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis.

  20876667   Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21060334   Genetic susceptibility to systemic lupus erythematosus in the genomic era.

  21326317   Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.

  21336280   Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.

  21362770   Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts.

  21622953   ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework.

  21750679   Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis.

  21905002   Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosus.

  22102179   Genetics of systemic sclerosis: an update.

  22174698   A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

  22407130   Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up.

  22488580   Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity.

  22531499   A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.

  22536486   Lupus nephritis: an overview of recent findings.

  22654485   Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  22924496   Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.

  23026857   The genetics of scleroderma: looking into the postgenomic era.

  23227085   Genetics of SLE: functional relevance for monocytes/macrophages in disease.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24489017   TNFAIP3 gene polymorphisms associated with differential susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Korean population.

  25328554   Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes.

  25337792   Genetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population.

  25569146   Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms.

  25777745   Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance.

  25806576   The polymorphisms of tumor necrosis factor-induced protein 3 gene may contribute to the susceptibility of chronic primary immune thrombocytopenia in Chinese population.

  26092158   IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups.

  26106387   Pathogenesis of Systemic Sclerosis.

  26663301   Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.

  26880555   Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.

  26997879   Genetic Susceptibility to Interstitial Lung Disease Associated with Systemic Sclerosis.

  27556446   Variations in the TNFSF4 gene are associated with early autoimmune thyroid disease and hypothyroidism in Hashimoto's thyroiditis.

  27726311   Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus risk: an updated meta-analysis.

  28434122   The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms.

  28448618   rs10499194 polymorphism in the tumor necrosis factor-α inducible protein 3 (TNFAIP3) gene is associated with type-1 autoimmune hepatitis risk in Chinese Han population.

  28526340   Unfolding the pathogenesis of scleroderma through genomics and epigenomics.

  29070082   Sex influences eQTL effects in SLE and genetic polymorphisms associated with Sjögren's syndrome.

  30041578   Association of ITGAM, TNFSF4, TNFAIP3 and STAT4 gene polymorphisms with risk of systemic lupus erythematosus in a North Indian population.

  30179587   Precision medicine in lupus nephritis: can biomarkers get us there?

  30770922   Genetics and epigenetics of primary Sjögren's syndrome.

  31217170   Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.

  33894768   Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes.

  35382378   Association of TNFAIP3 gene polymorphism (rs5029939) with susceptibility and clinical phenotype of systemic lupus erythematosus.

  35382527   Genetics of systemic sclerosis.