SNP information rs6445975

Research and publications:

  18853133   Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

  19225526   Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese.

  19442287   Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.

  19714582   Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors.

  20453842   Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

  20829310   Polymorphisms of PXK are associated with autoantibody production, but not disease risk, of systemic lupus erythematosus in Chinese mainland population.

  20848568   Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.

  20881011   Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21243490   Different genetic effect of PXK on systemic lupus erythematosus in the Korean population.

  21379322   Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

  21408207   Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

  21719445   Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.

  21792837   Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.

  21826374   Selective IgA deficiency in autoimmune diseases.

  21963258   Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets.

  22110124   Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.

  22174698   A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

  22291604   A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.

  22536486   Lupus nephritis: an overview of recent findings.

  22541939   Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study.

  22592861   Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.

  22640752   The genetics of lupus: a functional perspective.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  23049788   Further evidence of subphenotype association with systemic lupus erythematosus susceptibility loci: a European cases only study.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  24946689   Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25332064   An Immunochip-based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3.

  25862617   Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations.

  29070082   Sex influences eQTL effects in SLE and genetic polymorphisms associated with Sjögren's syndrome.