SNP information rs1801274

Research and publications:

  8636449   Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans.

  9843982   Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees.

  10675363   C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific.

  15367919   Fcgamma receptor IIA genotype and susceptibility to P. aeruginosa infection in patients with cystic fibrosis.

  15657875   Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.

  16846490   Lemierre's syndrome and genetic polymorphisms: case report

  16893392   The FCGR2A--Arg131 variant is no major mortality factor in the elderly--evidence from a German centenarian study.

  17018637   Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma

  17315188   Common variants in genes that mediate immunity and risk of multiple myeloma.

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17668374   Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants

  18194515   Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population

  18347005   Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.

  18418394   Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families.

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18759263   Features associated with, and the impact of, hemolytic anemia in patients with systemic lupus erythematosus: LX, results from a multiethnic cohort.

  18796628   Etiologic heterogeneity among non-Hodgkin lymphoma subtypes

  18936436   Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19140833   Linkage and association study of FcgammaR polymorphisms in celiac disease.

  19421223   Fcgamma receptors: structure, function and role as genetic risk factors in SLE.

  19545442   Marked differences in CRP genotype frequencies between the Fulani and sympatric ethnic groups in Africa.

  19640933   FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese.

  19838195   A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

  19898481   Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

  19915573   A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.

  19965803   FCGR2A functional genetic variant associated with susceptibility to severe malarial anaemia in Ghanaian children.

  20041166   Common genetic variation and the control of HIV-1 in humans

  20148910   Association of FcGRIIa with Graves' disease: potential role of dysregulated autoantibody clearance in disease onset/progression.

  20149216   Fcgamma receptor polymorphisms and their association with periodontal disease: a meta-analysis.

  20392289   Genetic associations in type I interferon related pathways with autoimmunity.

  20439102   Analysis of MIF, FCGR2A and FCGR3A gene polymorphisms with susceptibility to pulmonary tuberculosis in Moroccan population.

  20441431   Recent advances in the genetics of systemic lupus erythematosus.

  20508037   Copy number, linkage disequilibrium and disease association in the FCGR locus.

  20662065   Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.

  20691091   Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data.

  20848568   Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.

  20881011   Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.

  20941391   Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study

  21054877   Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994

  21060334   Genetic susceptibility to systemic lupus erythematosus in the genomic era.

  21068098   Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

  21109570   FcγR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer.

  21208440   Polymorphisms of Fcγ receptors CD16A and CD32 and circulating immune complexes in Meniere's disease: a case-control study.

  21250972   A pooled analysis of three studies evaluating genetic variation in innate immunity genes and non-Hodgkin lymphoma risk.

  21297633   Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

  21317643   The Fcγ receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia.

  21379322   Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

  21408207   Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

  21658613   Host genetics in follicular lymphoma.

  21719445   Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.

  21723269   Genetic profiling of GSTP1, DPYD, FCGR2A, FCGR3A and CCND1 genes in an Argentinian population.

  21737555   Genetic variants associated with severe pneumonia in A/H1N1 influenza infection.

  21768177   Is FCGR2A a susceptibility gene to systemic lupus erythematosus in Chinese?

  21780194   E-selectin rs5361 and FCGR2A rs1801274 variants were associated with increased risk of gastric cancer in a Chinese population.

  21792837   Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.

  21831733   Association of FCGR2A, JAK2 or HNF4A variants with ulcerative colitis in Koreans.

  21955043   Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort.

  22081228   Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease.

  22087647   Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population.

  22110124   Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.

  22113576   Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.

  22417159   DNA sequence variation and regulation of genes involved in pathogenesis of pulmonary tuberculosis.

  22446962   A genome-wide association study identifies three new risk loci for Kawasaki disease.

  22484354   Calcineurin inhibitor treatment of intravenous immunoglobulin-resistant Kawasaki disease.

  22486600   Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.

  22540264   The rs150311303 polymorphism in FcγRIIa enhances IgG binding capacity.

  22541939   Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study.

  22595970   Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

  22654485   Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing.

  22691414   Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  22879986   Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients.

  22905743   Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka.

  22922574   Fcγ receptor polymorphisms do not predict response to intravenous immunoglobulin in myasthenia gravis.

  22938532   Sequencing and analysis of a South Asian-Indian personal genome.

  22947458   Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso.

  22957039   Candidate polymorphisms and severe malaria in a Malian population.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  23049788   Further evidence of subphenotype association with systemic lupus erythematosus susceptibility loci: a European cases only study.

  23049979   Fc γ receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  23456091   Combined analysis of genome-wide-linked susceptibility loci to Kawasaki disease in Han Chinese.

  23459936   Exploring the genetic basis of chronic periodontitis: a genome-wide association study.

  23649770   Associations between FCGR2A rs1801274, FCGR3A rs396991, FCGR3B NA1/NA2 polymorphisms and periodontitis: a meta-analysis.

  23906684   Genetic associations with coronary heart disease: meta-analyses of 12 candidate genetic variants.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  24117665   Fc gamma receptor IIa-H131R polymorphism and malaria susceptibility in sympatric ethnic groups, Fulani and Dogon of Mali.

  24775607   Absence of association of FCGR2A gene polymorphism rs1801274 with Kawasaki disease in Greek patients.

  24911936   Contrasting associations of polymorphisms in FcγRIIa and DC-SIGN with the clinical presentation of dengue infection in a Mexican population.

  24946689   Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus.

  25093412   A genetic variant rs1801274 in FCGR2A as a potential risk marker for Kawasaki disease: a case-control study and meta-analysis.

  25116105   Human FcR polymorphism and disease.

  25294155   A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

  25645453   Systematic confirmation study of GWAS-identified genetic variants for Kawasaki disease in a Chinese population.

  25765626   Hardy-Weinberg equilibrium revisited for inferences on genotypes featuring allele and copy-number variations.

  25861330   Update of genetic susceptibility in patients with Kawasaki disease.

  26240159   Association of FcγRIIa Polymorphism with Clinical Outcome of Dengue Infection: First Insight from Pakistan.

  26314337   FCGR2A, FCGR3A, FCGR3B polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.

  26398853   Identification of Ten Additional Susceptibility Loci for Ulcerative Colitis Through Immunochip Analysis in Koreans.