SNP information rs1800629

Research and publications:

  12190096   A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism

  12759288   Genetic markers for the efficacy of tumour necrosis factor blocking therapy in rheumatoid arthritis

  12847678   Polymorphism at position -308 of the tumor necrosis factor alpha gene influences outcome of infliximab therapy in rheumatoid arthritis

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  15797957   Tumor necrosis factor-alpha polymorphism, bone strength phenotypes, and the risk of fracture in older women

  15817713   Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations

  15834068   Polymorphism at position -308 of the tumour necrosis factor alpha gene and rheumatoid arthritis pharmacogenetics

  15895461   TNF polymorphisms in Alzheimer disease and functional implications on CSF beta-amyloid levels

  16046815   Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes

  16385446   A testing framework for identifying susceptibility genes in the presence of epistasis

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  16617143   Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data

  16672072   The interferon gamma gene polymorphism +874 A/T is associated with severe acute respiratory syndrome

  16720636   The -308 tumour necrosis factor-alpha gene polymorphism predicts therapeutic response to TNFalpha-blockers in rheumatoid arthritis and spondyloarthritis patients

  16759385   Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

  16820586   Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery

  16846490   Lemierre's syndrome and genetic polymorphisms: case report

  16872485   Three allele combinations associated with multiple sclerosis

  16909270   Association of TNF-alpha -308 G/A polymorphism with responsiveness to TNF-alpha-blockers in rheumatoid arthritis: a meta-analysis

  17018637   Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma

  17054776   The genetics of chronic obstructive pulmonary disease

  17174749   Linkage disequilibrium with predisposing DR3 haplotypes accounts for apparent effects of tumor necrosis factor and lymphotoxin-alpha polymorphisms on type 1 diabetes susceptibility

  17216494   Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17343250   Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis

  17450233   Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma

  17510437   Immune mechanisms in non-Hodgkin lymphoma: joint effects of the TNF G308A and IL10 T3575A polymorphisms with non-Hodgkin lymphoma risk factors

  17668374   Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants

  17673491   A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis

  17701899   Flexible design for following up positive findings

  17705862   Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples

  18041006   Association of TGF-beta1 codon 25 (G915C) polymorphism with hepatitis C virus infection

  18050183   Influence of -308 A/G polymorphism in the tumor necrosis factor alpha gene on etanercept treatment in rheumatoid arthritis

  18194515   Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population

  18196539   TNF polymorphisms and prostate cancer risk

  18307517   Common studied polymorphisms do not affect plasma cytokine levels upon endotoxin exposure in humans

  18319718   Tumour-necrosis factor-A polymorphisms and gastric cancer risk: a meta-analysis

  18398712   No association found between the promoter variants of TNF-alpha and diabetic retinopathy in Chinese patients with type 2 diabetes

  18423522   Estimating odds ratios in genome scans: an approximate conditional likelihood approach

  18426866   Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort

  18434886   Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor

  18438841   Association between the level of circulating bioactive tumor necrosis factor alpha and the tumor necrosis factor alpha gene polymorphism at -308 in patients with rheumatoid arthritis treated with a tumor necrosis factor alpha inhibitor

  18513389   New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background

  18515978   Association of tumor necrosis factor -308G/A promoter polymorphism with schizophrenia and bipolar affective disorder in a Polish population

  18520591   Host cell factor C1 sequence variants are associated with Meniere's disease.

  18551993   SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women

  18575614   Association between LTA, TNF and AGER polymorphisms and late diabetic complications

  18603647   Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response

  18615156   Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis

  18620570   The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18635873   TNF promoter polymorphisms associated with muscle phenotypes in humans

  18640487   Association of donor inflammation- and apoptosis-related genotypes and delayed allograft function after kidney transplantation

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18698679   Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk

  18709160   Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease

  18713756   Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis

  18715339   Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population

  18796628   Etiologic heterogeneity among non-Hodgkin lymphoma subtypes

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  18811622   Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma

  18936436   Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

  18990758   Genetic variation in tumor necrosis factor and canonical nuclear factor-kappaB pathway and risk of non-Hodgkin's lymphoma

  19019335   Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants

  19035456   Adipokine genes and prostate cancer risk

  19035492   Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis

  19039607   A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19126646   Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA

  19131662   A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients

  19147066   Genomic and proteomic analysis of allogeneic hematopoietic cell transplant outcome. Seeking greater understanding the pathogenesis of GVHD and mortality

  19167443   Family-based analysis of tumor necrosis factor and lymphotoxin-alpha tag polymorphisms with type 1 diabetes in the population of South Croatia

  19225544   Variation in the lymphotoxin-alpha/tumor necrosis factor locus modifies risk of erythema nodosum in sarcoidosis

  19233472   Long-range linkage on chromosome 6p of VEGF, FKBP5, HLA and TNF alleles associated with transplant rejection

  19263529   Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach

  19279689   TNF-alpha -308 G>A and -238 G>A polymorphisms are not major risk factors in Caucasian patients with exfoliation glaucoma

  19281305   Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations

  19330901   Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study

  19347053   Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19365401   TNF-alpha-308 G/A polymorphism and responsiveness to TNF-alpha blockade therapy in moderate to severe rheumatoid arthritis: a systematic review and meta-analysis

  19386798   Relevance of gamma interferon, tumor necrosis factor alpha, and interleukin-10 gene polymorphisms to susceptibility to Mediterranean spotted fever

  19401444   Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism

  19405090   Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis

  19409079   Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study

  19419979   Preliminary evidence of a genetic association between tumor necrosis factor alpha and the severity of sleep disturbance and morning fatigue

  19438866   Polymorphisms in genes involved in DNA repair, cell growth, oxidative stress and inflammatory response, and melanoma risk

  19478423   Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels

  19505919   Toll-like receptor signaling pathway variants and prostate cancer mortality

  19559392   A candidate gene association study of 77 polymorphisms in migraine

  19615068   The role of TNF genetic variants and the interaction with cigarette smoking for gastric cancer risk: a nested case-control study

  19654554   The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma

  19661089   Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China

  19673019   IL-10 and TNF-alpha promoter haplotypes are associated with the location of Crohn's disease in children

  19700502   Synopsis and synthesis of candidate-gene association studies in chronic lymphocytic leukemia: the CUMAGAS-CLL information system

  19732761   Tumor necrosis factor alpha (TNF-alpha) polymorphism in Chinese patients with Graves' disease

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  19933216   The COPD genetic association compendium: a comprehensive online database of COPD genetic associations

  19934104   Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations

  19951401   Chronic obstructive pulmonary disease: towards pharmacogenetics