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SNP information rs2431697

RS2431697

Normal allele: CC

A functional variant of the microRNA-146a promoter modulates its expression and increases the risk of systemic lupus erythematosus.

Polymorphism rs2431697 is related to topics like this:

Lupus is it genetic

It is now well understood that lupus is caused by both environmental and genetic factors. At...


Research and publications:

  19440199   Recent insights into the genetic basis of systemic lupus erythematosus.

  20953187   Association analyses identify six new psoriasis susceptibility loci in the Chinese population.

  21068098   Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

  21408207   Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

  21738483   A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus

  22174698   A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

  22218224   Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene

  23252691   Investigation of 20 non-HLA (human leucocyte antigen) psoriasis susceptibility loci in Chinese patients with psoriatic arthritis and psoriasis vulgaris.

  24803388   Association of miR-146a polymorphisms with systemic lupus erythematosus: a meta-analysis.

  24991086   Novel insights into miRNA in lung and heart inflammatory diseases.

  25008481   Prognostic role of MIR146A polymorphisms for cardiovascular events in atrial fibrillation.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  25369137   A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene.

  26251230   Association between rs2431697 T allele on 5q33.3 and systemic lupus erythematosus: case-control study and meta-analysis.

  26366721   Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls.

  27635407   Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?

  27906046   Chromatin landscapes and genetic risk in systemic lupus.

  28470127   Polymorphisms associated with etanercept response in moderate-to-severe plaque psoriasis.

  28489066   Two Single Nucleotide Polymorphisms (rs2431697 and rs2910164) of miR-146a Are Associated with Risk of Coronary Artery Disease.

  28617847   The association between 38 previously reported polymorphisms and psoriasis in a Polish population: High predicative accuracy of a genetic risk score combining 16 loci.

  29437577   MiR-146a Regulates Neutrophil Extracellular Trap Formation That Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation.

  29902229   miR-146a deficiency in hematopoietic cells is not involved in the development of atherosclerosis.

  31235484   Association of microRNAs genes polymorphisms with arthritis: a systematic review and meta-analysis.

  32107471   miR-146a rs2431697 identifies myeloproliferative neoplasm patients with higher secondary myelofibrosis progression risk.

  32586906   miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis.

  32929657   Genetic variants of microRNA-146a gene: an indicator of systemic lupus erythematosus susceptibility, lupus nephritis, and disease activity.

  33294994   Associations between common genetic variants in microRNAs and Hirschsprung disease susceptibility in Southern Chinese children.

  33420081   SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression.

  33907143   Meta-analysis of association of microRNAs genetic variants with susceptibility to rheumatoid arthritis and systemic lupus erythematosus.

  34060972   Genetic variant in microRNA-146a gene is associated with risk of rheumatoid arthritis.

  34449663   Non-Coding Variants in Cancer: Mechanistic Insights and Clinical Potential for Personalized Medicine.

  34837916   Predictive Value of miR-146a rs2431697 Polymorphism to Myelofibrosis Progression in Patients with Myeloproliferative Neoplasm.

  35756164   mir-146a genetic polymorphisms in systemic lupus erythematosus patients: Correlation with disease manifestations.

  35887682   MiR-146a Contributes to Thromboinflammation and Recurrence in Young Patients with Acute Myocardial Infarction.

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