SNP information rs9888739

Research and publications:

  18853133   Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

  19129174   Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

  19286673   ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai.

  20629846   Association of ITGAM polymorphism with systemic lupus erythematosus: a meta-analysis.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21068098   Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

  21151989   Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

  21379322   Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

  21408207   Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

  21437871   Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus.

  22536486   Lupus nephritis: an overview of recent findings.

  22640752   The genetics of lupus: a functional perspective.

  22753952   Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  24871463   GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

  25034154   Clinical perspectives on lupus genetics: advances and opportunities.

  26798662   Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype.

  26880555   Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.

  27693588   Genetics of human lupus nephritis.

  29070082   Sex influences eQTL effects in SLE and genetic polymorphisms associated with Sjögren's syndrome.

  31659207   Rare variants in non-coding regulatory regions of the genome that affect gene expression in systemic lupus erythematosus.

  31774828   ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico.