SNP information rs1800630

Research and publications:

  12509789   Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis.

  17216494   Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17493155   Significant association between TNF-alpha (TNF) promoter allele (-1031C, -863C, and -857C) and cerebral malaria in Thailand.

  17595314   Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample.

  18194515   Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population

  18196539   TNF polymorphisms and prostate cancer risk

  18366708   SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis.

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18635873   TNF promoter polymorphisms associated with muscle phenotypes in humans

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18709160   Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19409079   Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study

  19505919   Toll-like receptor signaling pathway variants and prostate cancer mortality

  19615068   The role of TNF genetic variants and the interaction with cigarette smoking for gastric cancer risk: a nested case-control study

  19673019   IL-10 and TNF-alpha promoter haplotypes are associated with the location of Crohn's disease in children

  19673882   A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis.

  19933216   The COPD genetic association compendium: a comprehensive online database of COPD genetic associations

  20012999   The cancer anorexia/weight loss syndrome: exploring associations with single nucleotide polymorphisms (SNPs) of inflammatory cytokines in patients with non-small cell lung cancer

  20177654   Obesity-dependent association of TNF-LTA locus with type 2 diabetes in North Indians.

  20217072   SNP/haplotype associations in cytokine and cytokine receptor genes and immunity to rubella vaccine.

  20564140   Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors.

  20796230   Tumour necrosis factor-alpha gene polymorphisms and susceptibility to oral lichen planus.

  20825556   Tumour necrosis factor-α promoter region polymorphisms affect the course of spontaneous HBsAg clearance.

  21333900   The role of genetics in IBS

  21385363   Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study

  21450487   Tumor necrosis factor-α -863 C/A promoter polymorphism affects the inflammatory response after cardiac surgery.

  21708280   Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

  21756351   Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes.

  21904873   Association of tumor necrosis factor-α (TNF-α) promoter polymorphisms with overweight/obesity in a Korean population.

  21985478   TNFA-863 polymorphism is associated with a reduced risk of chronic obstructive pulmonary disease: a replication study.

  22001640   Tumour necrosis factor gene polymorphisms and migraine: a systematic review and meta-analysis.

  22121102   JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.

  22190997   Characterization of Single-Nucleotide Polymorphisms in the Tumor Necrosis Factor α Promoter Region and in Lymphotoxin α in Squamous Intraepithelial Lesions, Precursors of Cervical Cancer.

  22199996   Tumor necrosis factor-related genes and colon and rectal cancer.

  22230215   Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study.

  22487520   TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis.

  22666399   Tumor necrosis factor β-induced protein 8 polymorphism and the risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study.

  22711844   SNP in the TNF-α gene promoter associated with Behçet's disease in Moroccan patients.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  22947458   Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso.

  22969921   TNF-α -863 polymorphisms and the risk of hepatocellular carcinoma.

  23029405   Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.

  23049851   Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis.

  23050663   Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke.

  23057767   Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China.

  23133455   TNF-α Polymorphisms in Juvenile Idiopathic Arthritis: Which Potential Clinical Implications?

  23406059   Inflammatory factors gene polymorphism in recurrent oral ulceration.

  23895869   TNF-alpha promoter region polymorphisms affect HBV virus clearance in southern Chinese.

  24054031   Genetic variation in cytokine-related genes and migraine susceptibility.

  24151497   Analysis of the association of IL10, TNF-β and IL23R-IL12RB2 SNPs with the risk of Behçet's disease in Western Algeria.

  24281113   Inflammatory genetic markers of prostate cancer risk.

  24491308   Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men.

  24702779   Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia.

  24905365   TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.

  24936650   Association between tumor necrosis factor-α rs1800629 polymorphism and risk of asthma: a meta-analysis.

  24967817   Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

  24971461   Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort.

  24976707   Human genes involved in hepatitis B virus infection.

  25263964   Polymorphisms in the TNF-α, TNFR1 gene and risk of rheumatoid arthritis in Chinese Han population.

  25315199   Genetic association and gene expression studies suggest that genetic variants in the SYNE1 and TNF genes are related to menstrual migraine.

  25606441   In silico analysis of single nucleotide polymorphism (SNP) in human TNF-α gene.

  25636570   Association of TNF -1031 C/C as a potential protection marker for leprosy development in Amazonas state patients, Brazil.

  25652333   Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis.

  25704106   Association of tumor necrosis factor (TNF) promoter polymorphisms with plasma TNF-α levels and susceptibility to diabetic nephropathy in North Indian population.

  26088606   Tumour necrosis factor allele variants and their association with the occurrence and severity of malaria in African children: a longitudinal study.

  26418997   [Association of TNF-alpha and IL-13 genes polymorphisms with bronchial asthma].

  26601827   The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced PepticUlcers in a Korean Ethnic Group.

  26672513   Association between hepatocellular carcinoma and tumor necrosis factor alpha polymorphisms in South Korea.

  26690118   An Updated Review on the Genetics of Primary Open Angle Glaucoma.

  26751459   Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study.

  26872611   MAPK1/ERK2 as novel target genes for pain in head and neck cancer patients.

  26876219   Relationship of bovine TNF-α gene polymorphisms with the risk of bovine tuberculosis in Holstein cattle.

  27063995   Polymorphic Regions in Fc Gamma Receptor and Tumor Necrosis Factor-α Genes and Susceptibility to Chronic Periodontitis in a Cohort From South India.

  27111223   Serum Immunoglobulin G Levels to Porphyromonas gingivalis Peptidylarginine Deiminase Affect Clinical Response to Biological Disease-Modifying Antirheumatic Drug in Rheumatoid Arthritis.

  27186328   Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality.

  27547017   Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.

  27648002   Regulatory SNPs Alter the Gene Expression of Diabetic Retinopathy Associated Secretary Factors.

  28060727   Associations between genetic variants in immunoregulatory genes and risk of non-Hodgkin lymphoma in a Chinese population.

  28341818   Clinical Relevance of Cytokines Gene Polymorphisms and Protein Levels in Gingival Cervical Fluid from Chronic Periodontitis Patients.

  28740106   Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes.

  29027627   Association of TNF-α-3959T/C Gene Polymorphisms in the Chinese Population with Intracranial Aneurysms.

  29041886   [Polymorphisms in Genes of Cytokines and Matrix Metalloproteinases Associated With Ischemic Heart Disease in Patients With Type 2 Diabetes].

  29054398   Association of TNF-Alpha gene polymorphisms and susceptibility to hepatitis B virus infection in Egyptians.

  29230494   Association of polymorphisms in TNF and GRN genes with ankylosing spondylitis in a Chinese Han population.

  29409002   PTPN22 and CTLA-4 Polymorphisms Are Associated With Polyglandular Autoimmunity.

  29426041   Genetic Polymorphisms in Cytokine Genes in Colombian Patients with Ocular Toxoplasmosis.

  29449347   Association of tumor necrosis factor-α (TNF-α) gene promoter polymorphisms with aggressive and chronic periodontitis in the eastern Indian population.

  29706892   Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.

  30094865   Association of Interleukin-1 beta and tumor necrosis factor-alpha genetic polymorphisms with gastric cancer in India.

  30123371   Multiple Membrane Transporters and Some Immune Regulatory Genes are Major Genetic Factors to Gout.

  30662836   TNF-α gene polymorphisms: association with age-related macular degeneration in Russian population.

  30693270   Modeling Gene-Environment Interaction for the Risk of Non-hodgkin Lymphoma.

  30792445   Polymorphisms of cytokine genes and tuberculosis in two independent studies.

  30899307   Lack of association of -863C/A (rs1800630) polymorphism of tumor necrosis factor-a gene with rheumatoid arthritis.

  31001258   Proinflammatory Cytokine Gene Polymorphisms in Bullous Pemphigoid.

  31132515   Association of TNF-α gene alterations (c.-238G>A, c.-308G>A, c.-857C>T, c.-863C>A) with primary glaucoma in north Indian cohort.