Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Multiple sclerosis and see a list of existing studies.
SNP polymorphisms related to the topic Multiple sclerosis:
|The melastatin genetic variant plays a central role in magnesium homeostasis, which is critical for maintaining glucose and insulin metabolism.
|Serum levels of the chemokine CXCL13 associated with multiple sclerosis.
|A gene associated with vitamin D, serum vitamin D concentration and risk of multiple sclerosis.
|SH2D2A gene breakage may contribute to susceptibility to multiple sclerosis.
|LIGHT genetic variation is associated with susceptibility to multiple sclerosis.
|Slightly higher (1.08 times) risk of multiple sclerosis.
|Slight (1.4-fold) increase in risk of multiple sclerosis
|Increased risk of autoimmune diseases - systemic lupus erythematosus, vasculitis, celiac disease, and newly diagnosed diabetes mellitus after transplantation.
|Genetic heterogeneity of IL2RA indicates susceptibility to multiple sclerosis and susceptibility to type 1 diabetes.
|An additional locus of interest in multiple sclerosis.
|The CD58 genetic variant is associated with risk of multiple sclerosis and rheumatoid arthritis.
|Together with the rs4988889 gene breakage, it is a diagnostic criterion for celiac disease.
|Variation in the ATP-binding cassette transporter gene is significantly associated with susceptibility to multiple sclerosis (3-6 fold increase in risk).
|The major histocompatibility class I locus contributes to susceptibility to multiple sclerosis (3-6 times higher risk).
|Alteration of the interleukin 7 receptor (IL7R) alpha chain influences the risk of multiple sclerosis.
|Genetic association of TNFRSF1A variant with multiple sclerosis, odds ratio is 1.6
|Validation of IRF5 as a multiple sclerosis risk gene: putative role in human herpes virus-6 infection.
|CLEC16A variant, is associated with autoimmune diseases, particularly multiple sclerosis and type I diabetes.
|Polymorphisms associated with susceptibility to multiple sclerosis do not affect measures of disease severity.
|A variant of the ecotropic viral integration 5 (EVI5) gene is associated with multiple sclerosis.
|Variation in the IL7RA gene accounts for susceptibility to multiple sclerosis and type 1 diabetes.
|HLA DQ2.2 genes play an important role in many autoimmune diseases such as celiac disease, type 1 diabetes, rheumatoid arthritis, multiple sclerosis, psoriasis and others.
|Variations in the HHEX gene are associated with an increased risk of developing type 2 diabetes, affects acute glucose-stimulated insulin release.
|HLA-DPB1 gene polymorphism is associated with susceptibility to multiple sclerosis.
|CD86 polymorphism is associated with susceptibility to multiple sclerosis.
|Liver B1 kinase kinase polymorphism increases 2-fold risk of multiple sclerosis.
|The polymorphic locus rs10492972 of the KIF1B gene is associated with multiple sclerosis.
|Increased risk up to 1.4 times of multiple sclerosis disease.
|Polymorphisms influence the risk of developing type 1 diabetes.
|The IL2RA and IL7RA genes account for predisposition to multiple sclerosis.
|A rare coding variant of the IL22RA2 signalling peptide is associated with multiple sclerosis risk.
|A polymorphism in the MERTK receptor tyrosine kinase gene is associated with susceptibility to multiple sclerosis.
|Genetic variation in the IRF8 region is associated with Behcet's disease, multiple sclerosis and systemic lupus erythematosus.