SNP information rs4149584

Research and publications:

  11175303   Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a Dutch family: evidence for a TNFRSF1A mutation with reduced penetrance.

  19525953   Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  20362272   Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come.

  20405052   The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.

  20421368   Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.

  20430450   Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain.

  20811626   Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer

  21247752   Revealing the genetic basis of multiple sclerosis: are we there yet?

  21280076   Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.

  21431378   Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis.

  21523452   Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.

  21552549   The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study.

  22121102   JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.

  22199996   Tumor necrosis factor-related genes and colon and rectal cancer.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  23624563   TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  25326637   Clinical exome sequencing for genetic identification of rare Mendelian disorders.

  25333069   Disease variants in genomes of 44 centenarians.

  25866490   Genetic profiling of autoinflammatory disorders in patients with periodic fever: a prospective study.

  25988833   Analysis of the genetic basis of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome.

  26616867   Molecular dynamics and intracellular signaling of the TNF-R1 with the R92Q mutation.

  26839472   Clinical and Genetic Features of Korean Patients with Recurrent Fever and Multi-System Inflammation without Infectious or Autoimmune Evidence.

  28361096   Clinical dose effect and functional consequences of R92Q in two families presenting with a TRAPS/PFAPA-like phenotype.

  28927886   TNFRSF1A and MEFV mutations in childhood onset multiple sclerosis.

  30009568   TNFRSF1A polymorphisms and their role in multiple sclerosis susceptibility and severity in the Slovak population.

  30409984   Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics.

  30808881   Behçet's disease and genetic interactions between HLA-B*51 and autoinflammatory syndrome gene variants.

  31620089   Osteoporosis in Systemic Autoinflammatory Diseases: A Case-Control Study.

  32909274   Is gene panel sequencing more efficient than clinical-based gene sequencing to diagnose autoinflammatory diseases? A randomized study.

  35963536   Variant rs4149584 (R92Q) of the TNFRSF1A gene in patients with familial multiple sclerosis.